A nurse would expect to administer naloxone cautiously to which client?
- A. A client who is pregnant
- B. A client with cardiovascular disease
- C. A client with an alcohol dependency
- D. A client with an opioid dependency
- E. A client with chronic obstructive pulmonary disease
Correct Answer: A,B,D
Rationale: Opioid antagonists like naloxone (Narcan) should be used cautiously in those who are pregnant or lactating, in infants of opioid-dependent mothers, and in clients with an opioid dependency or cardiovascular disease.
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After administering naloxone to a client with respiratory depression, the nurse would expect to see the effects of the drug within which time frame?
- A. 1 to 2 minutes
- B. 3 to 4 minutes
- C. 5 to 6 minutes
- D. 7 to 8 minutes
Correct Answer: A
Rationale: Naloxone is capable of restoring respiratory function within 1 to 2 minutes after administration.
If time allows, the nurse should review which of the following with the client prior to administering an opioid antagonist?
- A. Initial health history
- B. Allergy history
- C. Bowel history
- D. Family medical history
- E. Current treatment modalities
Correct Answer: A,B,E
Rationale: If time allows, the nurse should review the client's initial health history, allergy history, and current treatment modalities prior to administering an opioid antagonist.
A nurse suspects that a client receiving naloxone is experiencing an adverse reaction when the assessment reveals which of the following?
- A. Bradycardia
- B. Dry, flushed skin
- C. Tremors
- D. Diarrhea
Correct Answer: C
Rationale: Generalized reactions to naloxone include nausea and vomiting, sweating, tachycardia, increased blood pressure, and tremors.
A nurse monitoring a client receiving naloxone (Narcan) should be cognizant for the development of which of the following adverse reactions?
- A. Nausea
- B. Constipation
- C. Tachycardia
- D. Hypotension
- E. Tremors
Correct Answer: A,C,E
Rationale: Generalized reactions that can occur with the use of opioid antagonists such as naloxone include nausea, vomiting, sweating, tachycardia, increased blood pressure, and tremors.
A nursing student is assigned to lead a class discussion on opioid antagonists. Which of the following would the student include as the mechanism by which opioid antagonists reverse the effects of opioid agonists?
- A. Competitive inhibition of the opioid receptor
- B. Direct binding to the opioid agonist
- C. Displacement of the opioid agonist from the opioid receptor
- D. Irreversible inhibition of the opioid receptor
- E. Mutation of the opioid receptor
Correct Answer: A,C
Rationale: Opioid agonists reverse the opioid effects by competing for the opiate receptor site and displacing the opioid drug.
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