Roach's Introductory Clinical Pharmacology 11th Edition - Cholinergic Blocking Drugs Related

Review Roach's Introductory Clinical Pharmacology 11th Edition - Cholinergic Blocking Drugs related questions and content

A nurse would monitor a client receiving a cholinergic blocking drug for an increased effect when the drug is administered with which of the following?

  • A. Fluconazole (Diflucan)
  • B. Meperidine (Demerol)
  • C. Haloperidol (Haldol)
  • D. Amitriptyline (Elavil)
  • E. Digoxin (Lanoxin)
Correct Answer: B,D

Rationale: A nurse may notice an increased effect of the cholinergic blocking drug when it is administered with meperidine (Demerol) and amitriptyline (Elavil) because meperidine and tricyclic antidepressants increase the effect of the cholinergic blockers.