A nurse would monitor a client receiving a cholinergic blocking drug for an increased effect when the drug is administered with which of the following?
- A. Fluconazole (Diflucan)
- B. Meperidine (Demerol)
- C. Haloperidol (Haldol)
- D. Amitriptyline (Elavil)
- E. Digoxin (Lanoxin)
Correct Answer: B,D
Rationale: A nurse may notice an increased effect of the cholinergic blocking drug when it is administered with meperidine (Demerol) and amitriptyline (Elavil) because meperidine and tricyclic antidepressants increase the effect of the cholinergic blockers.
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A nurse is administering glycopyrrolate to a client with a peptic ulcer. The nurse would assess the client for which of the following as a possible GI system adverse reaction?
- A. Diarrhea
- B. Dry mouth
- C. Constipation
- D. Nausea
- E. Dysphagia
Correct Answer: B,C,D,E
Rationale: A nurse administering glycopyrrolate to a client with a peptic ulcer should monitor the client for dry mouth, nausea, vomiting, constipation, and dysphagia.
If a cholinergic blocking drug is administered prior to surgery, which of the following would be most appropriate?
- A. Encourage the client to void after the drug is given.
- B. Tell the client that his mouth may feel dry.
- C. Allow the client to take sips of fluids.
- D. Have the client remain in bed after drug administration.
- E. Encourage the client to sit in the chair for about 30 minutes.
Correct Answer: B,D
Rationale: If a cholinergic blocking drug is administered prior to surgery, the nurse instructs the client to void before the drug is given, that an extremely dry mouth is normal but that no fluid should be ingested, and that the client should remain in bed, not sit in a chair.
A nurse is caring for a client admitted to the health care facility. The client is receiving a cholinergic blocking drug as treatment for bladder overactivity. Which intervention would be most appropriate for the nurse to include as part of the client's ongoing assessment?
- A. Assessment of the client's medical history
- B. Evaluation of symptoms related to the client's diagnosis
- C. Monitoring of the client's vital signs every 24 hours
- D. Observation for behavioral changes in the client
Correct Answer: B
Rationale: The nurse should evaluate the symptoms and complaints related to the client's diagnosis during the ongoing assessment of the treatment.
A client with an overactive bladder has been prescribed solifenacin by the physician. The client is also taking digoxin for the treatment of a cardiac condition. The nurse should monitor the client for an increase in which of the following resulting from the interaction of these two drugs?
- A. Increased neuromuscular blocking effect
- B. Increased effectiveness of digoxin
- C. Increased serum levels of digoxin
- D. Increased effectiveness of solifenacin
Correct Answer: C
Rationale: The nurse should monitor for increased serum levels of digoxin that occur due to the interaction of solifenacin and digoxin.
A nurse is caring for a client receiving cholinergic blocking drug therapy. The client complains of a cotton-mouth feeling. Which of the following would be most appropriate?
- A. Inspect the throat for signs of an infection.
- B. Suggest the client avoid ingesting water before taking the drug.
- C. Check the oral cavity daily for soreness or ulcerations.
- D. Suggest the client avoid the use of ice or cold beverages.
Correct Answer: C
Rationale: The nurse should check the oral cavity daily for soreness or ulcerations when caring for a client with severe mouth dryness.
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