A nursing instructor is evaluating the students' understanding of topical anti-infectives. The instructor determines that the group understands the information when they pair which drug with the infection treated correctly? Select all that apply.
- A. Erythromycin (Erygel) - acne vulgaris
- B. Ketoconazole (Nizoral) - episodes of HSV
- C. Ciclopirox (Loprox) - tinea pedis
- D. Acyclovir (Zovirax) - episodes of HSV
- E. Bacitracin (Baci-Rx) - tinea corporis
Correct Answer: A,C,D
Rationale: The following topical anti-infective drugs are matched correctly with the infection they treat: erythromycin (Erygel) - acne vulgaris; ciclopirox (Loprox) - tinea pedis; and acyclovir (Zovirax) - episodes of HSV.
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Chlorhexidine gluconate is being used in a client for preoperative skin preparation. Which of the following if noted would alert the nurse to a possible adverse reaction?
- A. Taste perversion
- B. Headache
- C. Deafness
- D. Mild erythema
Correct Answer: C
Rationale: The nurse should monitor for deafness as an adverse reaction to the use of chlorhexidine gluconate. Taste perversion, headache, and mild erythema are adverse reactions to penciclovir.
A client is diagnosed with dermatitis and the skin appears inflamed. Which topical drug would the nurse expect to administer to reduce itching, redness, and swelling caused by dermatitis? Select all that apply.
- A. Erythromycin (Erygel)
- B. Fluocinonide (Lidex)
- C. Penciclovir (Denavir)
- D. Imiquimod (Aldara)
- E. Hydrocortisone (Locoid)
Correct Answer: B,E
Rationale: Topical corticosteroids, like fluocinonide (Lidex) and hydrocortisone (Locoid), when applied to inflamed skin reduce itching, redness, and swelling caused by dermatitis.
A nurse administering collagenase (Santyl) topically to a client must be certain not to use which of the following products that can inactivate the enzymes in collagenase (Santyl)? Select all that apply.
- A. Detergents
- B. Water
- C. Iodine
- D. Silver
- E. Mercury
Correct Answer: A,D,E
Rationale: A nurse administering collagenase (Santyl) topically to a client must be certain not to use detergents or products containing heavy metals, like mercury and silver, which can inactivate the enzymes in collagenase (Santyl).
A client is prescribed topical benzocaine. The nurse would monitor the client for which of the following as a possible adverse reaction?
- A. Stinging, tenderness, and sloughing
- B. Erythema, flaking, and dryness
- C. Transient burning sensation
- D. Oiliness or dryness of hair
Correct Answer: A
Rationale: The nurse should monitor for stinging, tenderness, and sloughing in the client as adverse reactions to benzocaine. Erythema, flaking, and dryness are adverse reactions to masoprocol. A transient burning sensation is an adverse reaction to collagenase. Oiliness or dryness of the hair is an adverse reaction to selenium sulfide.
A client is prescribed a topical corticosteroid. Which of the following would be appropriate for the nurse to do?
- A. Clean the area with an antiseptic before applying the drug.
- B. Apply the topical corticosteroid sparingly.
- C. Place a sterile cloth over the area of application.
- D. Rub the application into the skin vigorously.
Correct Answer: B
Rationale: Topical corticosteroids should be applied sparingly to minimize systemic absorption and adverse effects. Cleaning with an antiseptic may not be necessary unless directed, and a sterile cloth or vigorous rubbing is not typically recommended.
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