Brunner & Suddarth's Textbook of Medical-Surgical Nursing 14e (Hinkle 2017) - Management of Patients With Immune Deficiency Disorders Related

Review Brunner & Suddarth's Textbook of Medical-Surgical Nursing 14e (Hinkle 2017) - Management of Patients With Immune Deficiency Disorders related questions and content

A patient has come into contact with HIV. As a result, HIV glycoproteins have fused with the patients CD4+ T-cell membranes. This process characterizes what phase in the HIV life cycle?

  • A. Integration
  • B. Attachment
  • C. Cleavage
  • D. Budding
Correct Answer: B

Rationale: During the process of attachment, glycoproteins of HIV bind with the hosts uninfected CD4+ receptor and chemokine coreceptors, which results in fusion of HIV with the CD4+ T-cell membrane. Integration, cleavage, and budding are steps that are subsequent to this initial phase of the HIV life cycle.