Nokea
A patient is being seen in the clinic for rheumatoid arthritis. Which of the following statements would indicate that she may be developing a complication from her rheumatoid medication, chloroquine (Aralen)?
- A. I have to urinate all the time.'
- B. Sometimes I have blurred vision.'
- C. I have tingling and numbness in my arms and legs.'
- D. Sometimes I feel like I am losing my balance when I walk.'
Correct Answer: B
Rationale: Chloroquine (Aralen) can cause ocular toxicity with blurring of vision, color vision changes, corneal damage, and blindness. Increased urination and tingling and numbness are signs of hyperkalemia and hypokalemia. Loss of balance can be caused by auditory damage due to drug toxicity.
You may also like to solve these questions
Pick the true statement:
- A. Amox- Clavulanic, Clavulanic increases amox activity
- B. Sublactum is used in treatment of Leprosy
- C. Aztreonam is a metabolite of clarithromycin
- D. Cilastatin imipenam- cilastatin prevents hydrolysis of imipenam
Correct Answer: B
Rationale: Sulbactam is used in leprosy treatment; other statements are incorrect (e.g., clavulanic enhances amoxicillin, cilastatin protects imipenem).
Clonidine has several off-label uses, including:
- A. Alcohol and nicotine withdrawal
- B. Post-herpetic neuralgia
- C. Both 1 and 2
- D. Neither 1 nor 2
Correct Answer: C
Rationale: Clonidine is used off-label for both alcohol/nicotine withdrawal and post-herpetic neuralgia.
A 19-year-old male was started on risperidone. Monitoring for risperidone includes observing for common side effects, including:
- A. Bradykinesia, akathisia, and agitation
- B. Excessive weight gain
- C. Hypertension
- D. Potentially fatal agranulocytosis
Correct Answer: A
Rationale: Risperidone frequently causes movement disorders like bradykinesia and akathisia.
Which of the following is used for the treatment of primary hyperaldosteronism:
- A. Furosemide
- B. Hydrocortisone
- C. Spironolactone
- D. Dexamethasone
Correct Answer: C
Rationale: Spironolactone is an aldosterone antagonist, making it effective for treating primary hyperaldosteronism by blocking excess aldosterone effects.
Which of the following drugs is used for the management of atropine intoxication?
- A. Physostigmine
- B. Neostigmine
- C. Endrophonium
- D. Donepezil
Correct Answer: A
Rationale: Physostigmine, a cholinesterase inhibitor, crosses the BBB to reverse atropine's central effects.