Nokea
A patient who is taking metronidazole (Flagyl) reports reddish-brown urine. Which action will the nurse take?
- A. Obtain an order for BUN and creatinine levels
- B. Reassure the patient that this is a harmless effect
- C. Request an order for a urinalysis
- D. Test her urine for occult blood
Correct Answer: B
Rationale: Reddish-brown urine is a benign metronidazole side effect; no labs are needed. Reddish-brown urine is a harmless side effect of metronidazole and is not cause for concern.
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A non-competitive antagonist :
- A. Alters the mechanism of action of an agonist
- B. Alters the potency of an agonist
- C. Shifts the dose-response curve of an agonist to the right
- D. Decreases the maximum response to an agonist
Correct Answer: D
Rationale: Non-competitive antagonists reduce the maximal response (efficacy), not potency, distinguishing them from competitive antagonists.
A nurse in the post-anesthesia recovery unit is caring for a client who received a nondepolarizing neuromuscular blocking agent and has muscle weakness. The nurse should anticipate a prescription for which of the following medications?
- A. Neostigmine
- B. Naloxone
- C. Dantrolene
- D. Vecuronium
Correct Answer: A
Rationale: Neostigmine reverses nondepolarizing neuromuscular blockers by increasing acetylcholine.
Half-lives of hydrophilic beta-blockers tend to be longer than their lipophilic counterparts.
- A. TRUE
- B. FALSE
Correct Answer: A
Rationale: Hydrophilic beta-blockers (e.g., atenolol) have longer half-lives due to renal elimination, unlike lipophilic ones (e.g., propranolol) metabolized by the liver.
A 27-year-old man is admitted to the emergency department (ED) after a serious motorcycle accident. The patient has a head injury, abrasions covering the left side of his body, a broken left femur, and internal injuries that are not fully assessed at this time. He is transferred from the ED to the intensive care unit (ICU). The nurse who is going to care for this patient in the ICU knows that a priority responsibility in regard to drug therapy is what?
- A. Support vital functions
- B. Continue curative treatment
- C. Institute life-saving treatment
- D. Monitor patient's response
Correct Answer: D
Rationale: Monitoring response ensures therapy adjusts to the patient's critical condition, a priority in ICU.
All the following induce hepatic enzymes except
- A. Rifampicin
- B. Phenytoin
- C. Barbiturates
- D. Tolbutamide
Correct Answer: D
Rationale: Tolbutamide does not significantly induce enzymes; others do.