A patient will be receiving diphenhydramine via a PEG tube, 25 mg, every 8 hours for an allergic rash. The medication is available as a 12.5 mg/5 mL syrup. Identify how many milliliters will the nurse administer with each dose.
Correct Answer: 10 mL
Rationale: 12.5 mg : 5 mL :: 25 mg : x mL; (12.5 * x) = (5 * 25); 12.5x = 125; x = 125/12.5 = 10 mL.
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A patient with a tracheostomy has difficulty removing excessive, thick mucus from the respiratory tract. The nurse expects that which drug will be ordered to aid in the removal of mucus?
- A. Guaifenesin
- B. Benzonatate
- C. Diphenhydramine
- D. Dextromethorphan
Correct Answer: A
Rationale: Expectorants such as guaifenesin work to loosen and thin sputum and the bronchial secretions, thereby indirectly diminishing the tendency to cough. The other drugs listed do not have this effect.
A patient has been advised to add an adrenergic decongestant nasal spray to treat a cold. The nurse will include which instruction?
- A. You won't see effects for at least 1 week.
- B. Limit use of this spray to 3 to 5 days.
- C. Continue the spray until nasal stuffiness has resolved.
- D. Avoid use of this spray if a fever develops.
Correct Answer: B
Rationale: Frequent, long-term, or excessive use of adrenergic nasal decongestants may lead to rebound congestion if used beyond the recommended time. The other instructions are incorrect.
A child will be receiving diphenhydramine (Benadryl), 5 mg/kg/day, in divided doses, every 6 hours. The child weighs 80 pounds. Identify how many milligrams of medication will the child receive with each dose.
Correct Answer: 45.5 mg
Rationale: 80 pounds ?· 2.2 = 36.36 kg, which rounds to 36.4 kg; 5 mg/kg/day ?? 36.4 kg = 182 mg/day. With doses given every 6 hours, there will be 4 total doses in a 24-hour period (24 ?· 6 = 4). To calculate milligrams per dose: 182 mg/day ?· 4 doses/day = 45.5 mg/dose.
A patient tells the nurse that she wants to start taking the herbal product goldenseal to improve her health. The nurse will assess for which potential cautions or contraindications to goldenseal?
- A. Taking a proton-pump inhibitor
- B. Nasal congestion
- C. Hypothyroidism
- D. Taking an antihypertensive drug
- E. Sinus infections
- F. Pregnancy
Correct Answer: A,D,F
Rationale: Goldenseal is contraindicated in patients with acute or chronic gastrointestinal disorders and during pregnancy (because it has uterine stimulant properties). It should be used with caution by those with cardiovascular disorders. Potential drug interactions may occur with gastric acid suppressors such as antacids, histamine H2 blockers (e.g., ranitidine), and proton-pump inhibitors (e.g., omeprazole), theoretically because of their reduced effectiveness resulting from the acid-promoting effect of the herb, and with antihypertensive drugs (because of the vasoconstrictive activity of the herb). Goldenseal is potentially useful for sinus infections and chronic nasal allergies.
A gardener needs a decongestant because of sinus problems and asks the nurse whether he should take an oral form or a nasal spray. Which of these is a benefit of orally administered decongestants?
- A. Immediate onset
- B. A more potent effect
- C. Lack of rebound congestion
- D. Shorter duration
Correct Answer: C
Rationale: Drugs administered by the oral route produce prolonged decongestant effects, but the onset of action is more delayed and the effect less potent than those of decongestants applied topically. However, the clinical problem of rebound congestion associated with topically administered drugs is almost nonexistent with oral dosage forms.
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