Nokea
A patient's preliminary diagnosis is toxoplasmosis. What material was used for diagnostics of this disease?
- A. Blood
- B. Feces
- C. Urine
- D. Duodenal contents
Correct Answer: A
Rationale: The correct answer is A: Blood. Toxoplasmosis is diagnosed through serological tests that detect specific antibodies in the blood. These antibodies indicate exposure to the Toxoplasma gondii parasite. Feces, urine, and duodenal contents are not typically used for diagnosing toxoplasmosis as the parasite is not commonly found in these samples. Blood is the primary material used as it provides the necessary antibodies for accurate diagnosis.
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The territory of an old burial ground for animal refuse that hasn't been used for over 50 years is meant for house building. But soil investigation showed the presence of viable spores of a causative agent causing a very dangerous disease. What microorganism might have been preserved in soil for such a long period of time?
- A. Bacillus anthracis
- B. Francisella tularensis
- C. Brucella abortus
- D. Yersinia pestis
Correct Answer: A
Rationale: The correct answer is A: Bacillus anthracis. This bacterium is known to form highly resistant spores that can survive for long periods in soil. Bacillus anthracis causes anthrax, a dangerous disease that can be transmitted to humans and animals. The other choices, Francisella tularensis, Brucella abortus, and Yersinia pestis, do not form spores as resistant as Bacillus anthracis. Therefore, only Bacillus anthracis is likely to have survived in the soil of the old burial ground for animal refuse for over 50 years.
Which bacteria is responsible for causing pneumonia?
- A. Streptococcus pneumoniae
- B. Mycobacterium tuberculosis
- C. Escherichia coli
- D. All of the above
Correct Answer: D
Rationale: The correct answer is D: All of the above. Streptococcus pneumoniae, Mycobacterium tuberculosis, and Escherichia coli can all cause pneumonia, but through different mechanisms. S. pneumoniae is a common cause of community-acquired pneumonia, M. tuberculosis can lead to tuberculosis-related pneumonia, and E. coli can cause pneumonia in immunocompromised individuals. Therefore, all three bacteria can be responsible for causing pneumonia, making option D the correct choice. Option A, Streptococcus pneumoniae, is correct but does not cover all possible causes of pneumonia. Option B, Mycobacterium tuberculosis, is too specific and does not include other common causes. Option C, Escherichia coli, is also a possible cause of pneumonia but does not account for all potential pathogens.
A 36-year-old man provisionally diagnosed with renal tuberculosis has undergone urinary sediment analysis. Microscopy revealed acid-fast bacteria, but Pryce method detected no cord factor. Name the most reliable method of investigation that can confirm or refute this provisional diagnosis:
- A. Inoculation of laboratory animals
- B. Phage typing of the obtained culture
- C. Allergy skin test
- D. Toxigenicity testing
Correct Answer: B
Rationale: The correct answer is B: Phage typing of the obtained culture. This method is used for typing Mycobacterium tuberculosis strains based on susceptibility to specific bacteriophages. If the culture shows susceptibility, it confirms the presence of M. tuberculosis. In this case, the absence of cord factor indicates that the bacteria are unlikely to be M. tuberculosis.
Option A (Inoculation of laboratory animals) is unethical and not necessary when other methods are available. Option C (Allergy skin test) is not relevant for confirming a diagnosis of renal tuberculosis. Option D (Toxigenicity testing) is not specific for confirming or refuting a diagnosis of M. tuberculosis.
Bacteriological examination of the urine of the patient with pyelonephritis revealed microorganisms that produced yellow-green pigment and a characteristic odor in meat-peptone agar. What are they called?
- A. Pseudomonas B.Escherichia C.Proteus D.Klebsiella E.Azotobacter
Correct Answer: A
Rationale: The correct answer is A: Pseudomonas. Pseudomonas bacteria are known to produce yellow-green pigment and a characteristic odor, specifically in meat-peptone agar. This is due to the production of pyoverdin pigment by Pseudomonas. Other choices like Escherichia, Proteus, Klebsiella, and Azotobacter do not typically produce yellow-green pigment or have a characteristic odor in meat-peptone agar. Therefore, based on the specific characteristics mentioned in the question, Pseudomonas is the most appropriate choice.
A patient suffers from pulmonary tuberculosis. During treatment neuritis of visual nerve arose. What drug has caused this by-effect?
- A. Isoniazid
- B. Ethambutol
- C. Kanamycin
- D. Rifampicin
Correct Answer: B
Rationale: The correct answer is B: Ethambutol. Ethambutol is known to cause optic neuritis, affecting the visual nerve. It is a well-documented side effect of this drug. Isoniazid (Choice A) is associated with peripheral neuropathy, not optic neuritis. Kanamycin (Choice C) is known for its side effects on the inner ear, causing hearing loss. Rifampicin (Choice D) is not typically associated with optic neuritis but can cause other adverse effects like hepatitis. By process of elimination and knowledge of drug side effects, Ethambutol is the most likely culprit.