A pharmaceutical lab states that a drug causes negative side effects in 3 of every 100 patients. To confirm this affirmation, another laboratory chooses 5 people at random who have consumed the drug. What is the probability that none of the five patients experience side effects?
- A. 0.8687
- B. 0.1313
- C. 0.00847
- D. 0.0003
Correct Answer: A
Rationale: Using the binomial distribution with n=5, p=0.03, and q=0.97, the probability of zero side effects is calculated as P(X=0) = (5 choose 0) * 0.97^5 = 0.8687, as shown in the document.
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Anticholinergic agents, such as benztropine (Cogentin), may be given with a phenothiazine to:
- A. Reduce the chance of tardive dyskinesia
- B. Potentiate the effects of the drug
- C. Reduce the tolerance that tends to occur
- D. Increase central nervous system 4 (iNS) rdey
Correct Answer: A
Rationale: Benztropine reduces EPS, which can precede tardive dyskinesia in phenothiazine use.
A nurse assessing a client's IV catheter insertion site notes a hematoma. Which of the following actions should the nurse take? (Select all that apply.)
- A. Stop the infusion.
- B. Apply alcohol to the insertion site.
- C. Apply warm compresses to the insertion site
- D. Lower the client's arm.
Correct Answer: C
Rationale: Warm compresses and elevation reduce swelling and promote absorption of a hematoma.
Which of the following drugs is considered a first-generation cephalosporin?
- A. Cefepime
- B. Cefazolin
- C. Ceftriaxone
- D. Cephalexin
Correct Answer: B
Rationale: Cefazolin is a first-generation cephalosporin, effective against Gram-positive bacteria, unlike cefepime (fourth) or ceftriaxone (third).
Immunomodulators such as azathioprine may cause a delayed adverse drug reaction known as a type D reaction because they are known:
- A. Teratogens
- B. Carcinogens
- C. To cause hypersensitivity reactions
- D. Hypothalamus-pituitary-adrenal axis suppressants
Correct Answer: B
Rationale: Azathioprine's Type D (delayed) ADRs, like cancer risk , emerge long-term, unlike teratogenicity , hypersensitivity , or HPA suppression .
Salicylic acid is prescribed for a client with a diagnosis of psoriasis. The nurse monitors the client, knowing that which of the following would indicate the presence of systemic toxicity from this medication?
- A. Tinnitus
- B. Diarrhea
- C. Constipation
- D. Decreased respirations
Correct Answer: A
Rationale: Salicylic acid is absorbed readily through the skin, and systemic toxicity (salicylism) can result. Symptoms include tinnitus, dizziness, hyperpnea, and psychological disturbances. Constipation and diarrhea are not associated with salicylism.