Nokea
A woman who was infected with toxoplasmosis during the pregnancy has a child with multiple congenital defects. This is a result of:
- A. Teratogenesis
- B. Cancerogenesis
- C. Recombination
- D. Chemical mutogenesis
Correct Answer: A
Rationale: The correct answer is A: Teratogenesis. Teratogenesis refers to the process of abnormal development of the fetus leading to congenital defects due to exposure to harmful agents during pregnancy. In this case, toxoplasmosis infection during pregnancy can lead to teratogenesis, causing multiple congenital defects in the child. Other choices are incorrect because B: Cancerogenesis refers to the process of cancer formation, C: Recombination is a genetic process unrelated to congenital defects, and D: Chemical mutagenesis refers to mutations caused by chemical agents, not necessarily congenital defects.
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The generation time of Escherichia coli is
- A. 20 min
- B. 60 min
- C. 20 hours
- D. 24 hours
Correct Answer: A
Rationale: The correct answer is A (20 min) because Escherichia coli typically has a generation time of around 20 minutes, meaning the time it takes for a bacterial population to double. This rapid reproduction rate is a key characteristic of E. coli. Option B (60 min) is incorrect as it is longer than the usual generation time. Option C (20 hours) is too long for E. coli's generation time. Option D (24 hours) is also incorrect as it is much longer than the typical generation time of E. coli.
A patient with diarrhea had stool culture revealing non-lactose-fermenting, Gram-negative rods. The bacteria produced gas in a nutrient broth. What is the most likely causative agent?
- A. Salmonella typhi
- B. Shigella dysenteriae
- C. Escherichia coli
- D. Proteus vulgaris
Correct Answer: D
Rationale: The correct answer is D: Proteus vulgaris. Non-lactose-fermenting, Gram-negative rods that produce gas in a nutrient broth are characteristic of Proteus species. Proteus vulgaris is known for its swarming motility and ability to produce hydrogen sulfide gas. Salmonella typhi and Shigella dysenteriae are Enterobacteriaceae that do not produce gas in a nutrient broth. Escherichia coli is a lactose-fermenting bacterium and would not be expected to produce gas in a nutrient broth.
The family Reoviridae includes the genera:
- A. Genus orthoreovirus, Rotavirus, Orbivirus
- B. Genus orthoretrovirus, Retrovirus, Orbfiloviridae
- C. Genus orthoretrovirus, Retrovirus, orbivirus
- D. Genus orthoretrovirus, Retrovirus, Orbarenaviridaefiloviridae
Correct Answer: A
Rationale: The correct answer is A because it lists the genera that belong to the family Reoviridae accurately. Orthoreovirus and Rotavirus are well-known genera within the family Reoviridae. Orbivirus is another genus belonging to the same family.
Choice B is incorrect because Orthoretrovirus and Retrovirus are not part of the Reoviridae family. Orbfiloviridae is also not a valid genus within this family.
Choice C is incorrect because Orthoretrovirus and Retrovirus are not part of the Reoviridae family. Orbivirus is the correct genus but the other two are inaccurate.
Choice D is incorrect because Orthoretrovirus and Retrovirus are not part of the Reoviridae family. Orbarenaviridaefiloviridae is not a valid genus within Reoviridae.
Microscopic examination of a Gramstained scrape from patient's tongue revealed oval, round, elongated chains of dark-violet gemmating cells. What disease can be caused by this causative agent?
- A. Candidosis
- B. Actinomycosis
- C. Diphtheria
- D. Staphylococcic infection
Correct Answer: A
Rationale: Step 1: Oval, round, elongated chains of gemmating cells indicate yeast-like budding cells seen in Candida species.
Step 2: Candidosis is caused by Candida species, which is commonly found in the oral cavity and can cause infections on the tongue.
Step 3: Candidosis presents as white patches or plaques on the tongue.
Step 4: Therefore, the correct answer is A: Candidosis.
Summary:
B: Actinomycosis is caused by Actinomyces species, which are filamentous bacteria, not oval budding cells.
C: Diphtheria is caused by Corynebacterium diphtheriae, which appears as gram-positive rods in chains, not oval budding cells.
D: Staphylococcal infections are caused by Staphylococcus species, which appear as clusters of cocci, not oval budding cells.
Hepatitis B infection may present with:
- A. Jaundice
- B. Elevated serum aminotransferase levels
- C. No symptoms
- D. All of the above
Correct Answer: D
Rationale: The correct answer is D: All of the above. Hepatitis B infection can present with jaundice due to liver inflammation, elevated serum aminotransferase levels due to liver damage, and sometimes no symptoms in the acute phase. This comprehensive presentation covers the spectrum of possible clinical manifestations of hepatitis B infection. Choices A and B are correct as they are common manifestations of hepatitis B infection. Choice C is incorrect as hepatitis B infection can indeed present with symptoms, making option D the most appropriate choice.