Nokea
Adverse effects of NSAIDs include:
- A. Acute renal dysfunction
- B. Renal papillary necrosis
- C. Fluid retention
- D. Hypokalaemia
Correct Answer: A
Rationale: NSAIDs can cause acute renal dysfunction by inhibiting prostaglandin synthesis, which is crucial for renal blood flow.
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Congenital toxoplasmosis is associated with:
- A. Microcephaly
- B. Chorioretinitis
- C. Sore throat
- D. Sacroileitis
Correct Answer: B
Rationale: Chorioretinitis is a common manifestation of congenital toxoplasmosis, often leading to vision problems and ocular abnormalities.
On examination, a nurse hears a murmur at the left sternal border (LSB) in a child with diarrhea and fever. The parent asks why the pediatrician never mentioned the murmur. The nurse explains:
- A. The pediatrician is not a cardiologist.
- B. Murmurs are difficult to detect, especially in children.
- C. The fever increased the intensity of the murmur.
- D. We need to refer the child to an interventional cardiologist.
Correct Answer: C
Rationale: The increased cardiac output associated with fever can accentuate a heart murmur, making it more noticeable.
A child can be diagnosed as having Kawasaki disease if he has:
- A. Fever > 3 days' duration, > 38°C
- B. Purulent conjunctivitis
- C. Thrombocytosis
- D. Polymorphous rash
Correct Answer: A
Rationale: Kawasaki disease is characterized by a fever lasting more than 3 days, which is a primary diagnostic criterion.
All the following antimalarials act by forming heme complexes which are toxic to the parasite except
- A. Primaquine
- B. Chloroquine
- C. Mefloquine
- D. Quinidine
Correct Answer: A
Rationale: Primaquine does not act by forming heme complexes; it works through a different mechanism.
The following antibodies are seen in the conditions mentioned:
- A. Anti-endomysial antibodies in coeliac disease
- B. Anti-insulin receptor antibodies in diabetes mellitus
- C. Anti-epidermal antibodies in vitiligo
- D. Anti-acetylcholine receptor antibodies in spinal muscular atrophy
Correct Answer: A
Rationale: Anti-endomysial antibodies are specifically associated with coeliac disease, making (a) the correct answer. The other options are incorrect as they describe antibodies associated with different conditions.