Nokea
Aldosterone:
Correct Answer: D
Rationale: Aldosterone is a hormone produced in the zona glomerulosa of the adrenal cortex, not the zona fasciculata (Choice A is incorrect). Conn's syndrome, also known as primary hyperaldosteronism, is characterized by excess aldosterone secretion, not a deficiency (Choice B is incorrect). Aldosterone production is under the control of the renin-angiotensin-aldosterone system, which is stimulated by factors such as low blood pressure, low blood volume, and high potassium levels. Elevated potassium in the blood directly suppresses aldosterone production by the adrenal glands, serving as a negative feedback mechanism to maintain electrolyte balance (Choice D is correct). The synthesis of aldosterone also requires cholesterol as the precursor, rather than pregnenolone (Choice E is incorrect). Lastly, aldosterone production is regulated in part by ACTH (adrenocorticotropic hormone), as it can enhance the effects of