Nokea
All are true about genotype - phenotype correlation in Brugada syndrome, except
- A. SCN5A mutation is associated with short PR interval
- B. LTCC mutation is associated with short QT interval
- C. Yield of genetic testing is low (25%)
- D. No major therapeutic implication of genetic testing
Correct Answer: D
Rationale: There are therapeutic implications of genetic testing in Brugada syndrome.
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Which of the following is correct in breast milk jaundice?
- A. Peaks at first week of life
- B. Recurs with resumption of breast milk after trial stoppage
- C. Kernicterus can occur
- D. Seen in up to 10% of infants
Correct Answer: B
Rationale: Breast milk jaundice recurs when breastfeeding is resumed after a temporary stoppage.
Hypertrophic obstructive cardiomyopathy
- A. Causes LV outflow tract obstruction
- B. Occurs after adenoviral infection
- C. Commonly occurs in infancy
- D. Double apical impulse
Correct Answer: A
Rationale: Hypertrophic obstructive cardiomyopathy primarily causes left ventricular outflow tract obstruction.
Contributing features to renal osteodystrophy include:
- A. Hypophosphataemia
- B. Hyperparathyroidism
- C. Increased loss of calcium in the kidney
- D. Hypoalbuminaemia
Correct Answer: B
Rationale: Hyperparathyroidism is a key contributor to renal osteodystrophy due to secondary hyperparathyroidism in chronic kidney disease.
The MOST common cyanotic congenital cardiac lesion to present in the newborn period is
- A. dextroposed heart
- B. transposition of great arteries
- C. tetralogy of Fallot
- D. truncus arteriosus
Correct Answer: B
Rationale: Transposition of the great arteries is the most common cyanotic congenital heart defect presenting in the neonatal period.
As part of the treatment for heart failure, the child takes the diuretic furosemide (Lasix). As part of teaching home care, the nurse encourages the family to give the child foods such as bananas, oranges, and leafy vegetables. These foods are recommended because they are high in which nutrient?
- A. Chlorides
- B. Potassium
- C. Sodium
- D. Vitamins
Correct Answer: B
Rationale: Diuretics that work on the proximal and distal renal tubules contribute to increased losses of potassium. The child’s diet should be supplemented with this electrolyte. With this type of diuretic, potassium must be monitored and supplemented as needed.