Nokea
All of following drugs are metabolized in body by acetylation except:
- A. INH
- B. Hydralazine
- C. Procainamide
- D. Dilantin
Correct Answer: D
Rationale: Dilantin (phenytoin) is metabolized by hydroxylation, not acetylation.
You may also like to solve these questions
The following adverse effects are associated with niacin EXCEPT:
- A. Flushing and itching
- B. Hypercuricemia
- C. Hyperglycemia
- D. Pellagra
Correct Answer: D
Rationale: Pellagra is caused by niacin deficiency, not an adverse effect of niacin therapy.
The nurse is caring for a patient who takes several drugs. What patient would the nurse monitor most closely because of an increased risk for adverse effects of medications?
- A. The school-aged child
- B. The obese middle-aged man
- C. The adolescent
- D. The newborn infant
Correct Answer: D
Rationale: Newborns have immature organs, increasing risk for adverse effects from multiple drugs.
What would the nurse provide when preparing a patient for discharge and home medication self-administration?
- A. Personal contact information to use if the patient has questions
- B. Thorough medication teaching about drugs and the drug regimen
- C. Over-the-counter medications to use to treat potential adverse effects
- D. A sample size package of medication to take home until prescription is filled
Correct Answer: B
Rationale: The nurse is responsible for providing thorough medication teaching about drugs and the drug regimen to ensure the patient knows how to take the medication and when to notify the provider. The nurse never provides personal contact information to a patient. If adverse effects arise, the patient is taught to call the health care provider and should not self-medicate with over-the-counter drugs, which could mask serious symptoms. The nurse never dispenses medication because it must be properly labeled for home use; this is done by the pharmacy.
Pharmacokinetics is:
- A. The study of biological and therapeutic effects of drugs
- B. The study of absorption, distribution, metabolism and excretion of drugs
- C. The study of mechanism of drugs
- D. The study of methods of new drug development
Correct Answer: B
Rationale: Pharmacokinetics focuses on how the body handles a drug, including absorption, distribution, metabolism, and excretion (ADME), distinguishing it from pharmacodynamics, which studies drug effects.
A low-carbohydrate, high-protein diet may:
- A. Increase drug-metabolizing enzymes
- B. Decrease drug absorption from the GI tract
- C. Alter drug binding to plasma proteins
- D. Enhance drug elimination
Correct Answer: A
Rationale: High-protein diets can induce hepatic enzymes (e.g., CYP450), increasing drug metabolism.