All the following are contents of space of Disse except:
- A. Pit cells
- B. Unmyelinated nerve fibers
- C. Ito cells
- D. Kupffer cells
Correct Answer: D
Rationale: Kupffer cells are in the sinusoidal lumen, not the space of Disse, which contains Ito cells, plasma, and microvilli.
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A 40-year-old patient presents with frequent episodes of heartburn, regurgitation, and a sour taste in the mouth after meals. Symptoms are worse when lying down or bending over. Which of the following conditions is the most likely cause of these symptoms?
- A. Gastric ulcer
- B. Hiatal hernia
- C. Pancreatitis
- D. Peptic esophagitis
Correct Answer: B
Rationale: Hiatal hernia allows acid reflux into the esophagus, worsened by lying down or bending, causing heartburn and regurgitation.
Micelle formation is necessary for the intestinal absorption of
- A. Galactose
- B. Vitamin B12
- C. Vitamin D
- D. Bile salts
Correct Answer: C
Rationale: Micelles, formed by bile salts, facilitate the absorption of fat-soluble vitamins like vitamin D in the small intestine.
Which gastric secretion is necessary for the absorption of vitamin B12 in the small intestine?
- A. Hydrochloric acid (HCl)
- B. Pepsinogen
- C. Intrinsic factor
- D. Mucus
Correct Answer: C
Rationale: Intrinsic factor, secreted by parietal cells in the stomach, binds to vitamin B12, enabling its absorption in the ileum of the small intestine.
How many nephrons are found in each kidney?
- A. approximately one hundred
- B. approximately one thousand
- C. approximately one million
- D. approximately ten million
Correct Answer: C
Rationale: Each kidney contains about one million nephrons, the functional units for filtration.
Secretion of enterogastrone would be stimulated by the presence of:
- A. protein in the small intestine
- B. protein in the stomach
- C. fat in the small intestine
- D. fat in the stomach
Correct Answer: C
Rationale: Enterogastrone secretion is triggered by fats in the small intestine to slow gastric emptying.