NCLEX RN Practice Questions PDF Related

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A.ls with leukemia is receiving Trimetrexate. After reviewing the client's chart, the physician orders Wellcovorin (leucovorin calcium). The rationale for administering leucovorin calcium to a client receiving Trimetrexate is to:

  • A. Treat iron-deficiency anemia caused by chemotherapeutic agents
  • B. Create a synergistic effect that shortens treatment time
  • C. Increase the number of circulating neutrophils
  • D. Reverse drug toxicity and prevent tissue damage
Correct Answer: D

Rationale: Leucovorin calcium is given as a rescue therapy to reverse the toxic effects of trimetrexate, protecting healthy cells from damage.