Nokea
Aminoglycosides work by irreversibly binding to the 30 ribosomal subunit.
- A. TRUE
- B. FALSE
Correct Answer: A
Rationale: Aminoglycosides irreversibly bind to the 30S ribosomal subunit, disrupting bacterial protein synthesis and leading to bactericidal effects.
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An elderly person has been prescribed lactulose for treatment of chronic constipation. Monitoring with long-term treatment would include:
- A. Electrolytes, including potassium and chloride
- B. Bone mineral density for osteoporosis
- C. Magnesium level
- D. Liver function
Correct Answer: A
Rationale: Lactulose can alter electrolytes (e.g., potassium) in the elderly; osteoporosis or magnesium aren't directly linked.
All of the following are adverse effects of phenothiazines except
- A. Rigidity and tremor
- B. Menstrual irregularities
- C. Cholestatic jaundice
- D. Systolic hypertension
Correct Answer: D
Rationale: Phenothiazines cause hypotension, not hypertension.
The following drug is not secreted in bile
- A. Penicillin
- B. Phenolphthalein
- C. Novobiocin
- D. Erythromycin
Correct Answer: A
Rationale: Penicillin is excreted via kidneys; others are secreted in bile.
A nurse working as a member of a research team is exploring the unique differences in drug response that each individual possesses based on his or her genetic makeup. This area of study is called:
- A. Pharmacotherapeutics
- B. Pharmacodynamics
- C. Pharmacoeconomics
- D. Pharmacogenomics
Correct Answer: D
Rationale: Pharmacogenomics is the area of study that includes mapping of the human genome. In the future, medical care and drug regimens may be personally designed based on a person's unique genetic makeup. Pharmacotherapeutics is the branch of pharmacology that deals with the use of drugs to treat, prevent, and diagnose disease. Pharmacodynamics involves how a drug affects the body. Pharmacoeconomics includes any costs involved in drug therapy.
Oral iron supplements are prescribed for a 6 year-old child with iron deficiency anemia. The nurse instructs the mother to administer the iron with which best food item?
- A. Milk
- B. Water
- C. Apple juice
- D. Orange juice
Correct Answer: D
Rationale: Vitamin C increases the absorption of iron by the body. The mother should be instructed to administer the medication with a citrus fruit or a juice that is high in vitamin C. Milk may affect absorption of the iron. Water will not assist in absorption. Orange juice contains a greater amount of vitamin C than apple juice.