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An adolescent girl asks the school nurse for advice because she has dysmenorrhea. She says that a friend recommended she try an over-the-counter nonsteroidal anti-inflammatory drug (NSAID). The nurse's response should be based on which statement?

  • A. Aspirin is the drug of choice for the treatment of dysmenorrhea.
  • B. Over-the-counter NSAIDs are rarely strong enough to provide adequate pain relief.
  • C. NSAIDs are effective because of their analgesic effect.
  • D. NSAIDs are effective because they inhibit prostaglandins, leading to reduction in uterine activity.
Correct Answer: D

Rationale: NSAIDs are effective for treating dysmenorrhea because they work by inhibiting prostaglandins, which are responsible for causing increased uterine activity and thus pain during menstruation. By reducing prostaglandin levels, NSAIDs help to decrease uterine contractions and consequently alleviate menstrual cramps. This mechanism of action makes NSAIDs an appropriate and effective choice for managing dysmenorrhea.