NCLEX RN Free Practice Questions Related

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An alcoholic client who is completing the inpatient segment of a substance abuse program was placed on disulfiram (Antabuse) drug therapy. What should the nurse include in the discharge instructions?

  • A. If disulfiram is taken and alcohol ingested, the client experiences nausea, vomiting and elevated blood pressure.
  • B. Disulfiram is most effective when prescribed as late as possible in a recovery program.
  • C. Disulfiram works on the desensitization principle.
  • D. The effects of disulfiram can be triggered by alcohol 5 days to 2 weeks after the drug is discontinued.
Correct Answer: D

Rationale: When alcohol is ingested with disulfiram therapy, the client experiences nausea, vomiting, and a potentially serious drop in blood pressure. Disulfiram is most successful when used early in the recovery process while the individual makes major lifestyle changes necessary for long-term recovery. Disulfiram works on the classical conditioning principle. The effects of disulfiram can be felt when alcohol is ingested 1-2 weeks after disulfiram is discontinued.