Nokea
Anthracycline (doxorubicin) on rare occasion causes acute inflammatory myocardial injury, but more classically results in dilated cardiomyopathy (DCM) in up to 30% of patients with a cumulative dose of doxorubicin exceeding
- A. 250 mg/m²
- B. 350 mg/m²
- C. 450 mg/m²
- D. 550 mg/m²
Correct Answer: D
Rationale: A cumulative dose of doxorubicin exceeding 550 mg/m² is associated with increased risk of dilated cardiomyopathy.
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A client returns to the unit following a suprapubic prostatectomy. He has a three-way catheter in place with a continuous bladder irrigation infusing. Which assessment finding warrants immediate intervention by the nurse?
- A. True urinary output of 50ml/hr
- B. Lower abdominal tenderness
- C. Blood urine output with clots
- D. Urine leaking around the meatus
Correct Answer: D
Rationale: Urine leaking around the meatus may indicate catheter displacement or obstruction, requiring immediate attention to prevent complications.
Recognised diagnoses of tender scrotal swelling in infancy include:
- A. Inguinal hernia
- B. Epididymo-orchitis
- C. Breech delivery
- D. Torsion of testis
Correct Answer: D
Rationale: Torsion of the testis is a medical emergency and a common cause of tender scrotal swelling in infancy. Inguinal hernia and epididymo-orchitis are also possible but less urgent. Breech delivery is unrelated.
FISH is helpful in diagnosing:
- A. Prader-Willi syndrome
- B. Di George syndrome
- C. Klinefelter's syndrome
- D. Turner's syndrome
Correct Answer: B
Rationale: FISH (Fluorescence In Situ Hybridization) is particularly useful in diagnosing DiGeorge syndrome, which involves microdeletions on chromosome 22.
Generalised absence seizures:
- A. Are usually atypical in type
- B. CT scan shows abnormalities in around 25-30% of cases
- C. Can be diagnosed in the absence of a typical EEG pattern with great certainty
- D. Are associated with other generalised seizures in most cases
Correct Answer: D
Rationale: Generalised absence seizures are often associated with other types of generalised seizures, such as tonic-clonic seizures.
Regarding diphtheria correct statement is
- A. Falling levels of immunity in the adult population is a reason for sporadic cases in the immunization era
- B. Immunization abolishes carrier state
- C. Antibiotic prophylaxis is not indicated for asymptomatic case contacts who are not carriers (negative cultures)
- D. Asymptomatic case contacts who are carriers should be administered antibiotic prophylaxis and antitoxin
Correct Answer: A
Rationale: Falling immunity levels in adults contribute to sporadic cases of diphtheria even in the immunization era.