Nokea
Antibodies against influenza viruses in a patient's serum can be determined by;
- A. Agglutination reaction
- B. Precipitation reaction in agar gel
- C. Reaction haemagglutination inhibition
- D. Ration haemagglutination
Correct Answer: C
Rationale: The correct answer is C: Reaction haemagglutination inhibition. This method is used to detect antibodies against influenza viruses by measuring the ability of the patient's serum to inhibit haemagglutination. This is a specific and sensitive technique for detecting influenza antibodies.
A: Agglutination reaction is not specific for influenza viruses and may give false positives.
B: Precipitation reaction in agar gel is not typically used for detecting influenza antibodies.
D: Ration haemagglutination is not a standard method for detecting influenza antibodies.
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Microscopic analysis of a smear stained by Ziehl-Neelsen method revealed bright red bacilli. What microorganism is being tested for?
- A. Mycobacterium tuberculosis
- B. Staphylococcus aureus
- C. Clostridium tetani
- D. Escherichia coli
Correct Answer: A
Rationale: The Ziehl-Neelsen stain is specific for acid-fast bacteria like Mycobacterium tuberculosis. The bright red bacilli seen in the smear indicate the presence of acid-fast organisms, which is characteristic of Mycobacterium tuberculosis. Staphylococcus aureus, Clostridium tetani, and Escherichia coli are not acid-fast bacteria and would not be stained red using the Ziehl-Neelsen method. Therefore, the correct answer is A: Mycobacterium tuberculosis.
Which of the following diseases is transmitted via aerosols?
- A. Psittacosis
- B. Shigellosis
- C. Leptospirosis
- D. Giardiasis
Correct Answer: A
Rationale: The correct answer is A: Psittacosis. This disease is transmitted via aerosols containing dried bird droppings or respiratory secretions from infected birds. When these aerosols are inhaled, the bacteria causing psittacosis enter the respiratory system and infect the individual.
- B: Shigellosis is transmitted through contaminated food or water, not via aerosols.
- C: Leptospirosis is transmitted through contact with water, soil, or food contaminated with the urine of infected animals, not via aerosols.
- D: Giardiasis is transmitted through ingesting contaminated food or water, not via aerosols.
Therefore, Psittacosis is the only disease in the list that is transmitted via aerosols, making it the correct answer.
Which of the following is a preferred mode of transmission of HIV from a mother to a child
- A. during delivery through mixing of blood
- B. during pregnancy through placenta
- C. via breastmilk during lactation
- D. All of the above
Correct Answer: D
Rationale: The correct answer is D because HIV can be transmitted from a mother to a child through multiple modes: during delivery through mixing of blood, during pregnancy through the placenta, and via breastmilk during lactation. Each mode presents a risk of transmission due to the presence of the virus in bodily fluids. Therefore, all of the above options are preferred modes of transmission for HIV from a mother to a child. Choices A, B, and C alone do not fully encompass all the possible routes of transmission, making them incorrect.
A sputum smear stained by Gram's method revealed Gram-positive cocci in clusters. The patient presented with an abscess. What is the causative agent?
- A. Staphylococcus aureus
- B. Streptococcus pyogenes
- C. Enterococcus faecalis
- D. Micrococcus luteus
Correct Answer: A
Rationale: The correct answer is A: Staphylococcus aureus. Staphylococcus aureus is a Gram-positive bacterium that commonly presents as cocci in clusters. It is a known causative agent of abscesses due to its ability to produce enzymes and toxins that contribute to tissue destruction. In this case, the presence of Gram-positive cocci in clusters aligns with the characteristic morphology of Staphylococcus aureus.
Summary of incorrect choices:
B: Streptococcus pyogenes is a Gram-positive bacterium that typically presents as cocci in chains, not clusters. It is more commonly associated with pharyngitis and skin infections rather than abscesses.
C: Enterococcus faecalis is a Gram-positive bacterium that typically presents as cocci in pairs or short chains, not clusters. It is more commonly associated with urinary tract infections and endocarditis.
D: Micrococcus luteus is a Gram-positive bacterium that typically presents as t
Which one is true for enteropathogenic E.coli?
- A. They have fimbrial adhesins to bind enterocytes
- B. They cause bloody diarrhea in children similar to shigellosis
- C. These organisms are part of the normal intestinal flora
- D. They are invasive and produce enterotoxin
Correct Answer: A
Rationale: The correct answer is A because enteropathogenic E. coli (EPEC) have fimbrial adhesins that help them bind to enterocytes in the intestines, leading to colonization and infection. This is a key virulence factor of EPEC.
Explanation for why other choices are incorrect:
B: EPEC typically cause watery diarrhea in infants, not bloody diarrhea similar to shigellosis.
C: EPEC are not part of the normal intestinal flora; they are pathogenic bacteria.
D: EPEC are not invasive and do not typically produce enterotoxin; they primarily adhere to the intestinal epithelium.