Nokea
Avascular necrosis of the femoral head is associated with:
- A. Sickle cell trait
- B. Nephrotic syndrome
- C. Cushing's syndrome
- D. Hypothyroidism
Correct Answer: C
Rationale: Cushing's syndrome is associated with avascular necrosis due to steroid use. Sickle cell trait, nephrotic syndrome, and hypothyroidism are not directly linked.
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The following are associated with an increased risk of fetal abnormalities:
- A. Oligohydramnios
- B. A previous sibling with anencephaly
- C. Paternal diabetes
- D. Decreased a-fetoprotein level
Correct Answer: B
Rationale: A previous sibling with anencephaly increases the risk of fetal abnormalities, particularly neural tube defects, in subsequent pregnancies.
Galactosaemia:
- A. Exhibits autosomal recessive inheritance
- B. Is associated with cataracts
- C. Results in a low glucose level
- D. Is due to an inability to convert galactose into glucose
Correct Answer: A
Rationale: Galactosaemia is an autosomal recessive disorder. It is associated with cataracts and results from the inability to convert galactose into glucose.
In Asia, the following hepatitis virus appears to be a significant cause of viral myocarditis
- A. hepatitis E virus
- B. hepatitis B virus
- C. hepatitis C virus
- D. hepatitis D virus
Correct Answer: A
Rationale: Hepatitis E virus has been identified as a significant cause of viral myocarditis in Asia.
All of the following are conditions with combined cellular and antibody immunodeficiency, except
- A. Ataxia telangiectasia
- B. Reticular dysgenesis
- C. Common variable immunodeficiency
- D. Severe combined immunodeficiency
Correct Answer: C
Rationale: Common variable immunodeficiency (CVID) is primarily an antibody deficiency, not a combined immunodeficiency.
Which of the following statements is true regarding alcohol septal ablation?
- A. Indicated when dynamic LV outflow gradient is more than 50 mm Hg at rest
- B. Targeted septal thickness less than 16 mm is a contraindication
- C. Usually preferred over surgical myomectomy
- D. Reduces risk of sudden death
Correct Answer: A
Rationale: Alcohol septal ablation is indicated when the dynamic LV outflow gradient is more than 50 mm Hg at rest.