Nokea
Bacterial ribosomes consist mainly of:
- A. Carbohydrates
- B. Lipids
- C. DNA
- D. rRNA
Correct Answer: D
Rationale: The correct answer is D: rRNA. Bacterial ribosomes consist mainly of ribosomal RNA (rRNA), which plays a crucial role in protein synthesis. Ribosomes are composed of rRNA and proteins, with rRNA being the major component. rRNA serves as the structural and catalytic component of the ribosome, aiding in the binding of mRNA and tRNA during translation. Carbohydrates (A) and lipids (B) are not primary components of ribosomes, and DNA (C) is not found in ribosomes as they are involved in storing genetic information, not in protein synthesis.
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A wound culture from a patient with an infected ulcer revealed Gram-positive cocci in clusters. The bacteria were catalase-positive and coagulase-negative. What is the most likely causative agent?
- A. Staphylococcus epidermidis
- B. Staphylococcus aureus
- C. Streptococcus pyogenes
- D. Enterococcus faecalis
Correct Answer: A
Rationale: The correct answer is A: Staphylococcus epidermidis. The presence of Gram-positive cocci in clusters, catalase-positive, and coagulase-negative characteristics indicate Staphylococcus species. Specifically, Staphylococcus epidermidis is a common skin commensal and a frequent cause of wound infections. Staphylococcus aureus is catalase-positive and coagulase-positive, making it less likely in this scenario. Streptococcus pyogenes and Enterococcus faecalis are both Gram-positive cocci but are catalase-negative, making them less likely causative agents.
A child cut his leg with a piece of glass while playing and was brought to the clinic for the injection of tetanus toxoid. In order to prevent the development of anaphylactic shock the serum was administered by Bezredka method. What mechanism underlies this method of desensitization of the body?
- A. Binding of IgE fixed to the mast cells
- B. Blocking the mediator synthesis in the mast cells
- C. Stimulation of immune tolerance to the antigen
- D. Stimulation of the synthesis of antigenspecific IgG
Correct Answer: A
Rationale: The correct answer is A: Binding of IgE fixed to the mast cells. The Bezredka method involves injecting small, gradually increasing doses of the antigen (tetanus toxoid) to desensitize the body and prevent anaphylactic shock. This process works by binding the IgE antibodies fixed to mast cells, thereby reducing the release of allergic mediators like histamine. This prevents the cascade of events that lead to anaphylactic shock.
Choice B (Blocking the mediator synthesis in the mast cells) is incorrect because the Bezredka method does not block mediator synthesis but rather prevents the release of mediators by binding IgE.
Choice C (Stimulation of immune tolerance to the antigen) is incorrect as the Bezredka method does not primarily focus on inducing immune tolerance but rather on preventing anaphylactic reactions.
Choice D (Stimulation of the synthesis of antigen-specific IgG) is incorrect because the Bezredka method targets IgE antibodies on mast cells
A 45-year-old patient has foul-smelling diarrhea. Stool examination revealed large ciliated protozoa with a kidney-shaped macronucleus. What is the causative agent?
- A. Balantidium coli
- B. Entamoeba histolytica
- C. Giardia lamblia
- D. Trichomonas hominis
Correct Answer: A
Rationale: The correct answer is A: Balantidium coli. This large ciliated protozoa with a kidney-shaped macronucleus is characteristic of Balantidium coli, an intestinal parasite known to cause foul-smelling diarrhea in humans. Balantidium coli is the only option among the choices that fits this specific description. Entamoeba histolytica causes amoebic dysentery, Giardia lamblia causes giardiasis, and Trichomonas hominis is a non-pathogenic protozoa found in the intestinal tract. Therefore, based on the morphology described in the question, Balantidium coli is the correct causative agent.
Gram-negative diplococci were isolated from a urethral discharge in a male patient with painful urination. What is the causative agent?
- A. Neisseria gonorrhoeae
- B. Escherichia coli
- C. Proteus vulgaris
- D. Klebsiella pneumoniae
Correct Answer: A
Rationale: The correct answer is A: Neisseria gonorrhoeae. This bacterium is a gram-negative diplococci commonly associated with gonorrhea, which presents with symptoms like painful urination. Neisseria gonorrhoeae is known to infect the urethra in males. Escherichia coli, Proteus vulgaris, and Klebsiella pneumoniae are all gram-negative bacteria, but they are not typically associated with urethral discharge or gonorrhea. E. coli is commonly associated with urinary tract infections, Proteus vulgaris with wound infections, and Klebsiella pneumoniae with pneumonia and other respiratory infections. Therefore, based on the patient's symptoms and the characteristics of the bacteria, Neisseria gonorrhoeae is the most appropriate causative agent in this case.
The development of polioviruses on cell cultures is characterized by:
- A. Cytopathic effect
- B. Cytotoxic effect
- C. Cytolytic effect
- D. They Don't Change The Cell Cultures
Correct Answer: A
Rationale: The correct answer is A: Cytopathic effect. This is because polioviruses cause visible changes in infected cells, leading to cell damage and death, known as cytopathic effect. This is a key characteristic of viral infection. Choice B (Cytotoxic effect) is incorrect as it refers to the toxicity of a substance to cells, not the specific effect of polioviruses. Choice C (Cytolytic effect) is incorrect as it specifically refers to cell lysis, which is not the primary mechanism of poliovirus infection. Choice D (They Don't Change The Cell Cultures) is incorrect because polioviruses do indeed cause changes in cell cultures due to their cytopathic effect.