Nokea
Because of the pattern of cholesterol synthesis, reductase inhibitors are given:
- A. In the evening in a single daily dose
- B. Twice daily in the morning and the evening
- C. With each meal and at bedtime
- D. In the morning before eating
Correct Answer: A
Rationale: Cholesterol synthesis peaks at night, so evening dosing optimizes reductase inhibitor efficacy.
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Which action will the nurse take when it is determined that the narcotic count is incorrect while obtaining a medication from the narcotic area?
- A. Determine the cause of the discrepancy at the end of the shift.
- B. Notify the health care provider stat.
- C. Call the nurse from the previous shift to determine if there was a discrepancy earlier.
- D. Report the discrepancy to the charge nurse immediately.
Correct Answer: D
Rationale: Reporting the discrepancy to the charge nurse immediately enables the supervisory staff to narrow the time frame during which a medication was taken and not documented. The discrepancy needs to be addressed immediately, and therefore determining the cause of the discrepancy at the end of the shift is not the most appropriate action for the nurse to take. It is not appropriate to contact the health care provider for an incorrect narcotic count. The count would have been verified at shift change; calling the nurse from the previous shift is not an appropriate action for the nurse to take.
Glibenclamide and chlorpropamide:
- A. Are well absorbed in Gl tract
- B. Increase release of endogenic insulin by pancreatic beta cells
- C. Is used as hormone replacement therapy for diabetes mellitus
- D. Is for internal use only
Correct Answer: B
Rationale: Glibenclamide and chlorpropamide increase endogenous insulin release from beta cells.
The patient tells the nurse about a new drug being tested to treat the disease she was diagnosed with and asks the nurse whether the doctor can prescribe a medication still in the preclinical phase of testing. What is the nurses best response?
- A. The doctor would have to complete a great deal of paperwork to get approval to prescribe that drug.
- B. Sometimes pharmaceutical companies are looking for volunteers to test a new drug and the doctor could give them your name.
- C. Drugs in the preclinical phase of testing are only tested on animals and so would not be available to you.
- D. Drugs in the preclinical phase of testing are given only to healthy young men and so would not be available to you.
Correct Answer: C
Rationale: During the preclinical phase of testing drugs are tested on animals and are not available to patients. In phase I, the drug is tested on volunteers who are usually healthy young men. It is only in phase III studies that the drug is made available to prescribers who agree to closely monitor patients getting the medication.
A young adult is receiving a maintenance dose of aminophylline, 3 mg/kg PO q6h. The patient weighs 50 kg. How much should the patient receive in a 24-hour period?
- A. 200 mg
- B. 400 mg
- C. 600 mg
- D. 800 mg
Correct Answer: C
Rationale: Use the formula, amount of drug prescribed weight of the patient in kg 4 (q6h in a 24-hour period = 4). 3 50 = 150 mg to be given every 6 hours. To determine how much the patient will receive in a 24-hour period, divide 6 into 24 to equal 4 doses. 4 150 = 600 mg.
When assessing a patient before starting a drug regimen, why would the nurse consider it important to assess baseline kidney function?
- A. To anticipate adverse effects of drugs
- B. To determine patient's baseline electrolyte levels
- C. To determine patient's ability to excrete the drug
- D. To determine patient's ability to metabolize the drug
Correct Answer: C
Rationale: Kidney function determines drug excretion, critical for dosing and avoiding toxicity.