Nokea
Besides osteoporosis, IV bisphosphonates are also indicated for:
- A. Paget's Disease
- B. Early osteopenia
- C. Renal cancer
- D. Early closure of cranial sutures
Correct Answer: A
Rationale: IV bisphosphonates treat Paget's disease by reducing bone turnover; osteopenia uses oral forms typically.
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Which of the following statements best defines how a chemical becomes a drug?
- A. A chemical must have a proven therapeutic value or efficacy without severe toxicity or damaging properties to become a drug.
- B. A chemical becomes a drug when it is introduced into the body to cause a change.
- C. A chemical is considered a drug when the Food and Drug Administration (FDA) approves its release to be marketed.
- D. A chemical must have demonstrated therapeutic value to become a drug.
Correct Answer: A
Rationale: A chemical must undergo a series of tests to determine its therapeutic value and efficacy without severe toxicity or damaging properties before it is termed a drug. Test results are reported to the FDA, which may or may not give approval.
Infants and young children are at higher risk of ADRs due to:
- A. Immature renal function in school-age children
- B. Lack of safety and efficacy studies in the pediatric population
- C. Children's skin being thicker than adults, it is less likely to absorb dosages of topical medication
- D. Infant boys having a higher proportion of muscle mass, leading to a higher volume of distribution
Correct Answer: B
Rationale: Lack of pediatric studies increases ADR risk due to unestablished safety/efficacy, unlike renal maturity , skin thickness (C, false), or muscle mass (D, false).
The Combination of amoxycillin + clavulanic acid is used because
- A. It broadens the spectrum of amoxycillin
- B. It decreases the side effect of amoxycillin
- C. It decreases the toxicity of clavulanic acid
- D. It increases the oral bio availability of amoxycillin
Correct Answer: A
Rationale: Clavulanic acid inhibits beta-lactamases, broadening amoxicillin's spectrum.
Which of the following is natural mineralcorticoid:
- A. Methylprednisolone
- B. Betamethasone
- C. Triamcinolone
- D. Aldosterone
Correct Answer: D
Rationale: Aldosterone is the natural mineralocorticoid produced by the adrenal glands.
The American Dietetic Association recommends pregnant women take a supplement including:
- A. 1,000 IU daily of vitamin D
- B. 2.4 mcg/day of vitamin B12
- C. 600 mcg/day of folic acid
- D. 8 mg/day of iron
Correct Answer: C
Rationale: 600 mcg/day of folic acid is recommended during pregnancy to prevent neural tube defects.