Concerning insulin-dependent diabetes mellitus in children:
- A. Microangiopathic changes are rare before puberty
- B. Isophane is shorter acting than soluble insulin
- C. Lipohypertrophy is more common than lipo-atrophy
- D. Fructosamine can be used to monitor glucose control
Correct Answer: A
Rationale: Microangiopathic changes are indeed rare before puberty in children with insulin-dependent diabetes mellitus. Isophane is not shorter acting than soluble insulin, and fructosamine is used to monitor glucose control.
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In the most common type of CAR:
- A. There is deficient 11-hydroxylase
- B. Hypertension is a feature
- C. There is an associated gene defect
- D. Transmission is autosomal dominant
Correct Answer: B
Rationale: Hypertension is a feature of congenital adrenal hyperplasia (CAH) caused by deficiencies in enzymes involved in steroidogenesis, including 11-hydroxylase.
The enzyme producing carbon monoxide within the human body is
- A. Aminolevulinic acid synthase
- B. Heme oxygenase
- C. Cyclo-oxygense
- D. Nitric oxide synthase
Correct Answer: B
Rationale: Heme oxygenase is responsible for the production of carbon monoxide during the breakdown of heme.
Causes of short stature include:
- A. Steroids at a dose of> 2 mg/kg for 4 weeks
- B. Osteogenesis imperfecta
- C. Hypochondroplasia
- D. Morquio syndrome
Correct Answer: A
Rationale: The correct answer is A because prolonged high-dose steroid use can cause growth suppression and short stature. The other options (b-e) are genetic or metabolic conditions that can also cause short stature.
Which statement by the mother of a child with rheumatic fever (RF) indicates that she has an understanding of prevention for her other children?
- A. “Whenever one of them gets a sore throat, I will give that child an antibiotic.â€
- B. “There is no treatment since it is viral and must run its course.â€
- C. “If their culture is positive for group A streptococcus, I will give them a full course of their antibiotic.â€
- D. “If their culture is positive for staphylococcus A, I will give them a full course of their antibiotic.â€
Correct Answer: C
Rationale: A positive culture for group A streptococcus indicates a bacterial infection that requires a full course of antibiotics to prevent rheumatic fever, which can develop as a complication of untreated strep throat.
The reason that the hematocrit is so high is
- A. chronic hypoxia
- B. it was taken in a low cardiac output state
- C. it was a peripheral finger stick
- D. embolic stroke
Correct Answer: A
Rationale: Chronic hypoxia leads to secondary polycythemia as a compensatory mechanism.