Medical Surgical NCLEX RN Related

Review Medical Surgical NCLEX RN related questions and content

Cortisone acetate (Cortone) and fludrocortisone acetate (Florinef Acetate) are prescribed as replacement therapy for a client with Addison's disease. What administration schedule should be followed for this therapy?

  • A. Take both drugs three times a day.
  • B. Take the entire dose of both drugs first thing in the morning.
  • C. Take all the fludrocortisone acetate and two-thirds of the cortisone acetate in the morning, and take the remaining cortisone acetate in the afternoon.
  • D. Take half of each drug in the morning and the remaining half of each drug at bedtime.
Correct Answer: C

Rationale: Mimicking diurnal cortisol patterns, most cortisone and all fludrocortisone are taken in the morning, with the remaining cortisone in the afternoon.