Drugs which increase GABA levels in brain
- A. Diazepam
- B. Phenobarbitone
- C. Sodium valproate
- D. Carbamazepine
Correct Answer: C
Rationale: Sodium valproate increases GABA levels.
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The intangible costs of drug therapy include:
- A. Loss of wages while undergoing therapy
- B. Inconvenience, pain, and suffering incurred with therapy
- C. Cost of medical equipment in the laboratory used to monitor therapeutic drug levels
- D. Cost of prescription drug coverage, such as Medicare Part D
Correct Answer: B
Rationale: Intangible costs are non-monetary, such as pain and suffering.
Elderly patients who are started on levothyroxine for hypothyroidism may experience which of the following as a side effect that would require reevaluation of dosage?
- A. Excessive sedation
- B. Tachycardia and angina
- C. Weight gain
- D. Cold intolerance
Correct Answer: B
Rationale: Levothyroxine can cause tachycardia and angina in the elderly if overdosed; sedation or weight gain suggest underdosing.
What does the nurse understand must occur in order to produce withdrawal syndrome?
- A. Addiction
- B. Craving
- C. Drug tolerance
- D. Physical dependence
Correct Answer: D
Rationale: Physical dependence causes withdrawal when a drug stops; addiction or tolerance don't suffice. Patients who develop a physical dependence on a drug will experience withdrawal syndrome when the drug is stopped.
You are doing an admission assessment on a patient. During the medication history portion of the assessment what would be important to assess with herbal supplements?
- A. Research them for interactions with other medications
- B. Discontinue them if taking prescription medications
- C. Take them one hour before prescription medications
- D. Take them three hours after prescription medications
Correct Answer: A
Rationale: Researching herbal interactions ensures safe integration with prescribed drugs, preventing adverse effects.
The following is the antithyroid mechanism of action of mercazolil:
- A. Inbits thyrotropic hormone production in pituitary
- B. Inhibits thyroid hormone synthesis in thyroid gland
- C. Interfere follicule cells in thyroid gland
- D. Interfere iod reaptake in thyroid gland
Correct Answer: B
Rationale: Mercazolil (methimazole) inhibits thyroid hormone synthesis by blocking thyroperoxidase activity in the thyroid.
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