Nokea
During latency, HSV1 exists in what form:
- A. Integrated in host chromosome
- B. Episomes in neurons
- C. No latency is established for that viral infection
- D. None of the above
Correct Answer: B
Rationale: During latency, HSV1 exists as episomes in neurons. This is because HSV1 establishes a lifelong latent infection in sensory neurons, where the viral genome remains as a circular episome in the nucleus. This form allows the virus to persist in a dormant state, avoiding detection by the immune system. Choice A is incorrect as HSV1 does not integrate into the host chromosome. Choice C is incorrect as latency is a well-documented phenomenon for HSV1. Choice D is incorrect as the correct answer is B.
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Micrographia, a publication illustrating insects, sponges, as well as plant cells, was published by
- A. Robert Hooke
- B. Antony van Leeuwenhoek
- C. Hans Janssen
- D. John Needham
Correct Answer: A
Rationale: The correct answer is A: Robert Hooke. Hooke published Micrographia in 1665, showcasing detailed illustrations of insects, sponges, and plant cells under the microscope. Hooke's work was groundbreaking in advancing the field of microscopy. Van Leeuwenhoek is known for discovering microorganisms but did not publish Micrographia. Janssen and Needham were not associated with Micrographia. Therefore, A is the correct answer.
Which of the following bacteria can produce endotoxins that cause septic shock?
- A. Escherichia coli
- B. Salmonella enterica
- C. Pseudomonas aeruginosa
- D. All of the above
Correct Answer: D
Rationale: The correct answer is D because all of the mentioned bacteria (Escherichia coli, Salmonella enterica, and Pseudomonas aeruginosa) are gram-negative bacteria that produce endotoxins in their cell walls. Endotoxins are released when the bacteria are destroyed, leading to the activation of the immune system and potentially causing septic shock. Escherichia coli and Salmonella enterica are common causes of gastrointestinal infections, while Pseudomonas aeruginosa is known for causing infections in immunocompromised individuals. Therefore, all three bacteria can produce endotoxins that contribute to septic shock. Choices A, B, and C are incorrect because each of these bacteria individually can produce endotoxins that lead to septic shock.
What is the structure of bacterial flagella?
- A. 9+2 microtubule arrangement
- B. protein filaments made of flagellin
- C. lipid bilayer
- D. peptidoglycan layer
Correct Answer: B
Rationale: The correct answer is B: protein filaments made of flagellin. Bacterial flagella are composed of flagellin proteins arranged in helical filaments. This structure allows for movement and propulsion of bacteria.
A: 9+2 microtubule arrangement is incorrect because this structure is typically found in eukaryotic flagella, not bacterial flagella.
C: Lipid bilayer is incorrect as it is a structural component of cell membranes, not bacterial flagella.
D: Peptidoglycan layer is incorrect as it is a component of bacterial cell walls, not flagella.
Which of the following bacteria is known for causing the disease tetanus?
- A. Clostridium tetani
- B. Clostridium perfringens
- C. Streptococcus pyogenes
- D. Escherichia coli
Correct Answer: A
Rationale: The correct answer is A: Clostridium tetani. This bacterium is known for causing tetanus due to its ability to produce tetanospasmin, a neurotoxin that leads to the characteristic muscle stiffness and spasms seen in tetanus. Clostridium perfringens (Choice B) is associated with gas gangrene, Streptococcus pyogenes (Choice C) causes streptococcal infections, and Escherichia coli (Choice D) is known for causing various gastrointestinal infections. Therefore, Choices B, C, and D are incorrect as they are not the causative agents of tetanus.
A fecal sample cultured on Endo agar revealed colorless colonies. The bacteria were Gram-negative rods and lactose non-fermenters. What microorganism is most likely?
- A. Salmonella
- B. Escherichia coli
- C. Shigella
- D. Proteus
Correct Answer: C
Rationale: The correct answer is Shigella (Choice C) because it matches the description of being Gram-negative rods and lactose non-fermenters. Shigella is a non-lactose fermenting, Gram-negative rod that typically produces colorless colonies on Endo agar. Salmonella (Choice A) and Escherichia coli (Choice B) are both lactose fermenters and would produce pink colonies on Endo agar. Proteus (Choice D) is also a lactose fermenter and would appear pink on Endo agar. Therefore, based on the characteristics provided, Shigella is the most likely microorganism in this scenario.