Nokea
Family Reoviridae does not include:
- A. Orthoreovirus type 3
- B. Orthomyxovirus type 1
- C. Orthoreovirus type 1
- D. Orthoreovirus type 2
Correct Answer: B
Rationale: The correct answer is B: Orthomyxovirus type 1. Family Reoviridae includes Orthoreovirus types 1, 2, and 3. Orthomyxovirus belongs to a different family, Orthomyxoviridae. Therefore, B is the correct answer. Orthoreovirus types 1, 2, and 3 are part of the Reoviridae family. Choice A, C, and D are incorrect because they are all part of the Reoviridae family which includes Orthoreoviruses.
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The innate immune system is always working to protect the body and does not require any special preparation to stop infection:
- A. TRUE
- B. FALSE
- C. Both answers can be correct depending on the given situation
- D. None of the above
Correct Answer: A
Rationale: The correct answer is A: TRUE. The innate immune system is the body's first line of defense against infections and is always active, providing immediate protection without prior exposure to a specific pathogen. It includes physical barriers, such as skin and mucous membranes, and cellular components like phagocytes and natural killer cells. The innate immune response is nonspecific and rapid, providing a crucial initial defense against pathogens.
Choice B is incorrect because the innate immune system is always active, even without any prior exposure to pathogens. Choice C is incorrect because the innate immune system is consistently functioning to protect the body, regardless of the situation. Choice D is incorrect as the correct answer is A.
The movement of molecules through a membrane from an area of high hydrostatic pressure to an area of lower hydrostatic pressure is:
- A. filtration
- B. exocytosis
- C. simple diffusion
- D. simple diffusion
Correct Answer: D
Rationale: The correct answer is D: simple diffusion. In simple diffusion, molecules move from an area of high concentration to low concentration without the need for energy input. Hydrostatic pressure is a form of passive transport that drives molecules to equalize concentration. Filtration (A) involves the movement of solutes through a membrane under pressure. Exocytosis (B) is the process by which cells release substances outside the cell using energy. Osmosis (C) is the movement of water molecules across a selectively permeable membrane. Therefore, simple diffusion is the most appropriate choice in this scenario.
Listeria monocytogenes are:
- A. Gram-negative rod-shaped bacteria
- B. Gram-positive spherical bacteria
- C. Gram-positive rod-shaped bacteria
- D. None of the above
Correct Answer: C
Rationale: The correct answer is C: Gram-positive rod-shaped bacteria. Listeria monocytogenes is a Gram-positive bacterium, as it retains the crystal violet stain during the Gram staining process. The bacteria are rod-shaped, not spherical. Choice A is incorrect as Listeria monocytogenes is not Gram-negative. Choice D is incorrect as Listeria monocytogenes does fall under the category of Gram-positive bacteria. The key is to remember the characteristics of Listeria monocytogenes, which are Gram-positive and rod-shaped.
After a prolonged isoniazid treatment, the patient developed polyneuritis, paresthesia, memory disorders, and convulsions. What is the most likely mechanism of the described isoniazid side-effects?
- A. Disruption of cell membrane synthesis
- B. Inhibition of protein synthesis
- C. Inhibition of RNA-synthesis
- D. Inhibition of pyridoxal phosphate synthesis
Correct Answer: D
Rationale: The correct answer is D. Isoniazid inhibits pyridoxal phosphate synthesis, which is the active form of vitamin B6. Pyridoxal phosphate is essential for various enzymatic reactions, including neurotransmitter synthesis and myelin formation. Therefore, isoniazid-induced pyridoxal phosphate deficiency can lead to neurological symptoms like polyneuritis, paresthesia, memory disorders, and convulsions.
A: Disruption of cell membrane synthesis - This is not the mechanism of isoniazid side-effects.
B: Inhibition of protein synthesis - Isoniazid does not directly inhibit protein synthesis.
C: Inhibition of RNA-synthesis - Isoniazid does not inhibit RNA synthesis; it affects vitamin B6 metabolism.
Which form of human plague is present with high fever and large lymphadenopathies (buboes). The case fatality in untreated cases may reach 60%.
- A. Bubonic plague
- B. Pneumonic plague
- C. Gastrointestinal plague
- D. Septicemic plague
Correct Answer: A
Rationale: The correct answer is A: Bubonic plague. Bubonic plague is characterized by high fever and large swollen lymph nodes (buboes). The case fatality rate in untreated cases can reach 60%. This form of plague is typically transmitted through the bite of an infected flea.
B: Pneumonic plague presents with respiratory symptoms and is transmitted through respiratory droplets.
C: Gastrointestinal plague is not a recognized form of plague.
D: Septicemic plague is a severe form of plague where the bacteria multiply in the bloodstream. It may not always present with buboes.