Following are the true receptors, except one
- A. Beta adrenergic receptors
- B. Na-K-ATP ase
- C. Phosphodiesterase
- D. Plasma proteins
Correct Answer: D
Rationale: Plasma proteins bind drugs but are not receptors.
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Which of the following regarding E max is correct?
- A. E max assumes that as long as you increase the concentration of the drug, there will be a higher effect of the drug
- B. E max is used to compare the potency of different drugs
- C. E max assumes that all receptors are occupied by the drug and no increase in response is observed if a higher concentration of drug is obtained
- D. All of the previous points are incorrect
Correct Answer: C
Rationale: Emax is the maximal effect when all receptors are occupied; further dose increases yield no additional effect.
Brands of pancreatic enzyme replacement drugs are:
- A. Bioequivalent
- B. About the same in cost per unit of lipase across brands
- C. Able to be interchanged between generic and brand-name products to reduce cost
- D. None of the above
Correct Answer: D
Rationale: Pancreatic enzymes vary in potency and aren't bioequivalent or interchangeable ; cost differs .
A patient with a new onset of systolic ejection murmur should be assessed for which nutritional deficiency?
- A. Vitamin B12
- B. Vitamin C
- C. Folate
- D. Niacin
Correct Answer: A
Rationale: Vitamin B12 deficiency can lead to anemia, potentially causing a systolic murmur.
Patients prescribed aspirin therapy require education regarding the signs of aspirin toxicity. An early sign of aspirin toxicity is:
- A. Black tarry stools
- B. Vomiting
- C. Tremors
- D. Tinnitus
Correct Answer: D
Rationale: Tinnitus is an early aspirin toxicity sign; black stools or vomiting are later.
A nurse is caring for a patient taking multiple drugs and is concerned about a possible drug-drug interaction. What is the nurse's first and best means of avoiding this problem?
- A. Consult a drug guide.
- B. Call the pharmacist.
- C. Contact the provider.
- D. Ask another nurse.
Correct Answer: A
Rationale: Whenever two or more drugs are being given together, first consult a drug guide for a listing of clinically significant drug-drug interactions. Sometimes problems can be avoided by staggering the administration of the drugs or adjusting their dosages. Consulting the pharmacist is not wrong, but it would not be the first action to take. The nurse holds responsibility for his or her own practice so asking a health care provider or another nurse is based on the assumption that that professional is knowledgeable about all drug-drug interactions, which is likely not the case.