Nokea
Following drugs have disulfiram-like reaction when taken with alcohol EXCEPT
- A. Sulfonylureas
- B. Amoxicillin
- C. Metronidazole
- D. Cefoperazone
Correct Answer: B
Rationale: Metronidazole, cefoperazone, and some sulfonylureas cause a disulfiram-like reaction (flushing, nausea) with alcohol by inhibiting aldehyde dehydrogenase; amoxicillin does not.
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Cynthia is taking valproate (Depakote) for seizures and would like to get pregnant. What advice would you give her?
- A. Valproate is safe during all trimesters of pregnancy.
- B. She can get pregnant while taking valproate, but she should take adequate folic acid.
- C. Valproate is not safe at any time during pregnancy.
- D. Valproate is a known teratogen, but may be taken after the first trimester if necessary.
Correct Answer: D
Rationale: Valproate is teratogenic (e.g., neural tube defects) but may be used post-first trimester if essential.
Which of the following is an insulin effect in the liver:
- A. Inhibition of glycogenolisis
- B. Inhibition of glycolysis
- C. Decrease of glycogenesis
- D. Decreases of pyruvatkinase, phosphofructokinase and glucokinase activity
Correct Answer: A
Rationale: Insulin inhibits glycogenolysis in the liver, promoting glucose storage as glycogen rather than its breakdown.
The decision may be made to switch from twice daily neutral protamine Hagedorn (NPH) insulin to insulin glargine to improve glycemia control throughout the day. If this is done:
- A. The initial dose of glargine is reduced by 20% to avoid hypoglycemia
- B. The initial dose of glargine is 2 to 10 units per day
- C. Patients who have been on high doses of NPH will need tests for insulin antibodies
- D. Obese patients may require more than 100 units per day
Correct Answer: A
Rationale: Switching to glargine reduces the dose by 20% to prevent hypoglycemia due to its steady action vs. NPH peaks.
Which of the following is true regarding the Dietary Supplement Health and Education Act (DSHEA)?Select one that does not apply.
- A. The act allows for DEA enforcement of the act.
- B. The act gives the FDA power to enforce the laws governed by the act.
- C. The act permits general health claims.
- D. The act does not permit curative health claims.
Correct Answer: A
Rationale: The DSHEA defines substances such as herbs, vitamins, minerals, amino acids, and other natural substances as 'dietary supplements' and permits general health claims as long as the label also has a disclaimer stating that the supplements are not approved by the FDA and are not intended to diagnose, treat, cure, or prevent any disease. The act gives the FDA the power to enforce the laws governed by the act.
The nurse is conducting an admission assessment on a patient. When collecting data related to medications the nurse asks, What medications are you currently taking? After collecting this information, what other questions should the nurse ask?
- A. Do you take any medications?
- B. What over-the-counter (OTC) medications do you take?
- C. Do you take gym sessions?
- D. Do you take medications safely when you take them?
Correct Answer: B
Rationale: OTC meds and supplements can affect therapy; 'current medications' already covers A, and D is vague.