Nokea
Hemolytic anaemia is characterised by:
- A. Increased haptoglobin
- B. Haemosiderinuria
- C. Polychromasia
- D. Megaloblastic bone marrow
Correct Answer: B
Rationale: Haemosiderinuria: Hemolytic anaemia often leads to the release of heme, which is broken down into hemosiderin, leading to haemosiderinuria (presence of hemosiderin in urine).
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Common presenting features of myotonic dystrophy are:
- A. Floppy infant
- B. Corneal opacities
- C. Frontal baldness
- D. Macro-orchidism
Correct Answer: D
Rationale: Macro-orchidism: Myotonic dystrophy is characterized by muscle weakness and myotonia. Macro-orchidism (enlarged testes) is a distinctive feature, especially in male patients.
In childhood, hypokalaemic alkalosis is a recognised finding:
- A. In a baby given feeds that are too concentrated
- B. In congenital pyloric stenosis
- C. In cystic fibrosis
- D. Following urinary diversion
Correct Answer: B
Rationale: Hypokalaemic alkalosis is a hallmark of congenital pyloric stenosis due to vomiting. It is not typically associated with concentrated feeds, cystic fibrosis, or urinary diversion.
Measuring serum potassium is essential in a child with confirmed hypertension because hyperkalemia may be seen in
- A. Liddle syndrome
- B. Gordon syndrome
- C. glucocorticoid remediable aldosteronism
- D. apparent mineralocorticoid excess
Correct Answer: D
Rationale: Hyperkalemia is not typically associated with Liddle syndrome, which causes hypokalemia.
A 12-month-old infant who had cardiopulmonary bypass with RBC and plasma infusions during surgery at 8 months is seen for a well child examination. Which vaccine may be administered at this visit?
- A. Measles
- B. mumps
- C. and rubella (MMR)
- D. Oral polio vaccine (OPV)
Correct Answer: C
Rationale: Live vaccines should be delayed until 6 months after cardiopulmonary bypass and exposure to RBCs and plasma. PCV-13 is not a live-virus vaccine.
Most common autoimmune antibody - mediated encephalopathy is
- A. Anti-NMDA receptor antibody syndrome
- B. Anti-voltage gated potassium channel antibody syndrome
- C. Anti-AMPAR antibody syndrome
- D. Anti-Glycine receptor antibody syndrome
Correct Answer: A
Rationale: Anti-NMDA receptor antibody syndrome is the most common autoimmune antibody-mediated encephalopathy.