Herbs and supplements are regulated by the U.S. Food and Drug Administration.
- A. TRUE
- B. FALSE
Correct Answer: B
Rationale: Herbs and supplements are not regulated as drugs by the FDA; they fall under dietary supplement rules.
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Which of the following is a disadvantage of IM administration?
- A. Larger volumes can be used
- B. Can affect lab tests
- C. Painful
- D. B and C
Correct Answer: C
Rationale: Intramuscular (IM) administration is painful due to needle insertion, though larger volumes are an advantage; affecting lab tests is less specific, making C the primary disadvantage.
A nurse is providing teaching for a client who has a new prescription for Metformin. Which of the following adverse effects of Metformin should be correct the client to report to the provider?
- A. Somnolence
- B. Constipation
- C. Fluid retention
- D. Weight gain
Correct Answer: A
Rationale: Somnolence could indicate lactic acidosis, a rare but serious metformin side effect to report.
Which of the following is the mechanism of action of iodides:
- A. Inhibits organification of iodine
- B. By inhibiting \mathrm{Na}+/ \mathrm{l} - simporter reduce iodine transport in thyroid gland
- C. Inhibits production of trioodthyronine form tetraiodthyronine on periphery
- D. Stimulates peroxidase
Correct Answer: A
Rationale: Iodides inhibit iodine organification, reducing thyroid hormone synthesis in high doses.
The choice of diuretic to use in treating hypertension is based on:
- A. Presence of diabetes with loop diuretics being used for these patients
- B. Level of kidney function with a thiazide diuretic being used for an estimated glomerular filtration rate higher than the mid-40 mL/min range
- C. Ethnicity with aldosterone antagonists best for African Americans and older adults
- D. Presence of hyperlipidemia with higher doses needed for patients with LDL above 130 mg/dL
Correct Answer: B
Rationale: Thiazides are effective with GFR >40-50 mL/min; loops are used for lower GFR.
A nurse is planning to administer a first dose of Captopril to a client who has hypertension. Which of the following medications can intensify first dose hypotension? (Select one that does not apply.)
- A. Simvastatin
- B. Hydrochlorothiazide
- C. aliskiren
- D. Clonidine
Correct Answer: A
Rationale: Diuretics , clonidine , and aliskiren enhance hypotension with captopril's first dose.
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