Nokea
Hormones may be used in cancer therapy, especially for advanced disease. Which of the following are hormones used as antineoplastic drugs? Select all that apply.
- A. Testolactone (Teslac)
- B. Leuprolide (Lupron)
- C. Megestrol (Megace)
- D. Bicalutamide (Casodex)
- E. Goserelin (Zoladex)
Correct Answer: A,B,C,E
Rationale: Testolactone (Teslac), leuprolide (Lupron), megestrol (Megace), and goserelin (Zoladex) are hormones used as antineoplastic drugs. Bicalutamide (Casodex) is an antiandrogen, not a hormone.
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A client is prescribed flavoxate. When reviewing the client's history, the nurse would expect to find which of the following complaints? Select all that apply.
- A. Dysuria
- B. Nocturia
- C. Leakage
- D. Suprapubic pain
- E. Inability to void
Correct Answer: A,B,D
Rationale: Flavoxate, an antispasmodic, is used to relieve symptoms of dysuria, urinary urgency, nocturia, suprapubic pain, and frequency and urge incontinence. Other antispasmodics are used to treat bladder instability, such as leakage caused by a neurogenic bladder. The drug is not used to treat an inability to void.
A client comes to the emergency department and reports that he is in extreme pain. Physical assessment reveals priapism. When obtaining the client's medication history, which of the following would the nurse expect the client to report using?
- A. Tamsulosin
- B. Terazosin
- C. Tadalafil
- D. Tolterodine
Correct Answer: C
Rationale: Priapism occurs with the use of phosphodiesterase type 5 inhibitors, such as tadalafil. It is not associated with use of antiadrenergic drugs or antispasmodics.
After teaching a group of nursing students about drugs used to treat genitourinary problems in the older adult, the instructor determines that the teaching was successful when the students identify which of the following as an alpha-adrenergic blocker used to treat BPH? Select all that apply.
- A. Darifenacin
- B. Oxybutynin
- C. Alfuzosin
- D. Tamsulosin
- E. Raloxifene
Correct Answer: C,D
Rationale: Alpha-adrenergic drugs used to treat BPH include alfuzosin and tamsulosin. Darifenacin and oxybutynin are antispasmodics. Raloxifene is a miscellaneous agent used to prevent and treat osteoporosis.
A nurse is caring for a client receiving goserelin acetate for prostate cancer. The nurse would monitor the client for which of the following adverse reactions?
- A. Breast atrophy, sexual dysfunction
- B. Pharyngitis, asthenia
- C. Breast tenderness, edema
- D. Hyperglycemia, leukocytosis
Correct Answer: A
Rationale: Breast atrophy and sexual dysfunction may be seen as adverse reactions of goserelin acetate therapy. Pharyngitis and asthenia are seen with the use of anastrozole, Breast tenderness and edema are seen with drugs such as estramustine. Hyperglycemia and leukocytosis are seen as adverse reactions of mitotane.
A client is receiving estrogen therapy but also takes phenytoin for seizure control. The nurse would alert the client to the possibility of which of the following?
- A. Potential for blood clots
- B. Increased risk for infection
- C. Possibility of breakthrough bleeding
- D. Increased risk for seizures
Correct Answer: C
Rationale: When estrogen is given with phenytoin, a hydantoin, the client is at increased risk for breakthrough bleeding. Blood clots can be an adverse reaction with estrogen therapy alone. There is no increased risk for infection. When given together, these drugs do not increase the risk for seizures.