Human immune globulin intravenous (IGIV) products have been associated with renal problems. The nurse understands that which clients should not receive IGIV? Select all that apply.
- A. Clients with diabetes mellitus
- B. Clients 65 years of age or older
- C. Clients receiving vancomycin
- D. Clients with pre-existing renal disease
- E. Clients receiving cephalexin
Correct Answer: A,B,C,D
Rationale: IGIV is contraindicated in clients with diabetes, those 65 or older, those with pre-existing renal disease, or those receiving nephrotoxic drugs like vancomycin.
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A nurse is educating a group of nursing students about the immediate reactions that may occur after administering antivenins. Within which of the following time periods will the immediate reaction be seen if the client is sensitive to the antivenin?
- A. 30 minutes
- B. 60 minutes
- C. 90 minutes
- D. 120 minutes
Correct Answer: A
Rationale: Immediate hypersensitivity reactions to antivenins typically occur within 30 minutes.
Vaccines containing live organisms are not administered to clients taking which of the following drugs as insufficient numbers of antibodies are produced to prevent the disease because these drugs suppress the immune system? Select all that apply.
- A. Methylprednisolone (Medrol)
- B. Ciprofloxacin (Cipro)
- C. Prednisolone (Orapred)
- D. Paclitaxel (Taxol)
- E. Vincristine (Oncovin)
Correct Answer: A,C,D,E
Rationale: Live vaccines are contraindicated with corticosteroids (methylprednisolone, prednisolone) and antineoplastic drugs (paclitaxel, vincristine) due to immune suppression.
After teaching a group of nursing students about the various immunologic drugs, the instructor determines that the teaching was successful when the students identify which of the following as a viral vaccine? Select all that apply.
- A. Haemophilus influenza type B conjugate
- B. Typhoid
- C. Mumps
- D. Avian influenza
- E. Rabies
Correct Answer: C,D,E
Rationale: Mumps, avian influenza, and rabies are viral vaccines.
A nurse is preparing to administer an immunologic drug that produces active immunity. Which of the following might the nurse be administering? Select all that apply.
- A. Vaccines
- B. Antibodies
- C. Toxoids
- D. Antigens
- E. Immune globulin
Correct Answer: A,C
Rationale: Both vaccines and toxoids are administered to stimulate the body's immune response to specific antigens or toxins, producing active immunity.
Which of the following is an example of artificially acquired active immunity? Select all that apply.
- A. An individual who is exposed to chickenpox for the first time and has no immunity to the disease
- B. Administration of the varicella vaccine to an individual who has no immunity to the disease
- C. An individual who is exposed to pertussis for the first time and has no immunity to the disease
- D. Administration of the influenza vaccine to an individual who has no immunity to the disease
- E. Administration of the rubella vaccine to an individual who has no immunity to the disease
Correct Answer: B,D,E
Rationale: Artificially acquired active immunity occurs when an individual is given a killed or weakened antigen, which stimulates the formation of antibodies against the antigen. The antigen does not cause the disease, but the individual still manufactures specific antibodies against the disease.
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