In a cyanotic spell of TOF
- A. Systemic vascular resistance is reduced
- B. Murmur disappear
- C. PO2 is reduced
- D. Right to Left shunt is Increased
Correct Answer: D
Rationale: During a cyanotic spell in Tetralogy of Fallot, there is an increased right-to-left shunting through the ventricular septal defect.
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Urinary tract infection:
- A. Usually leads to vesico-ureteric reflux
- B. Is more common in boys than girls under a year of age
- C. In boys,is most commonly caused by Proteus mirabilis
- D. Is associated with constipation
Correct Answer: D
Rationale: Urinary tract infections (UTIs) are often associated with constipation in children, as stool retention can increase the risk of bacterial colonization in the urinary tract.
Indications for surgical closure of a VSD include the following EXCEPT
- A. patients who cannot thrive
- B. patients whose symptoms cannot be controlled between 6 and 24 months
- C. patients with pulmonary vascular disease
- D. patients older than 2 years with a large VSD associated with a Qs ratio greater than 2:1
Correct Answer: C
Rationale: Surgical closure is not routinely indicated for all VSDs, especially if asymptomatic.
Clinical manifestations of haemophilia include:
- A. Bleeding following neonatal intramuscular injection
- B. Intracranial bleeding
- C. Gingival bleeding
- D. Menorrhagia
Correct Answer: B
Rationale: Intracranial bleeding is a serious and potentially life-threatening manifestation of hemophilia, particularly in severe cases.
Which is the most common causative agent of bacterial endocarditis?
- A. Staphylococcus albus
- B. Streptococcus hemolyticus
- C. Staphylococcus albicans
- D. Streptococcus viridans
Correct Answer: D
Rationale: S. viridans is the most common causative agent in bacterial (infective) endocarditis.
The following enzymes and inhibitors are matched correctly:
- A. Xanthine oxidase-allopurinol
- B. Enolase-fluoride
- C. Cholinesterase-physostigmine
- D. Ceruloplasmin-penicillamine
Correct Answer: A
Rationale: Xanthine oxidase-allopurinol: Allopurinol inhibits xanthine oxidase, which plays a role in purine metabolism, and is used to treat gout and prevent uric acid buildup.