In childhood asthma:
- A. Over 90% of patients show exercise-induced bronchoconstriction
- B. Hypercapnia is the first physiological disturbance in status asthmaticus
- C. Infants are unresponsive to bronchodilators
- D. Spontaneous cure occurs before adolescence
Correct Answer: D
Rationale: Spontaneous cure before adolescence is a recognized phenomenon in childhood asthma, though not all cases resolve. Other options are incorrect: exercise-induced bronchoconstriction is common but not universal, hypercapnia occurs late in status asthmaticus, and infants do respond to bronchodilators.
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Proteins found in muscle fibres include:
- A. Vimentin
- B. Saccharin
- C. Keratin
- D. Desmin
Correct Answer: D
Rationale: Desmin: Desmin is an intermediate filament protein found in muscle fibers, playing a critical role in maintaining structural integrity and organization within muscle cells.
A child has been diagnosed with valvular disease following rheumatic fever (RF). During patient teaching, the nurse discusses the child's long-term prophylactic therapy with antibiotics for dental procedures, surgery, and childbirth. The parents indicate they understand when they say:
- A. She will need to take the antibiotics until she is 18 years old.
- B. She will need to take the antibiotics for 5 years after the last attack.
- C. She will need to take the antibiotics for 10 years after the last attack.
- D. She will need to take the antibiotics for the rest of her life.
Correct Answer: D
Rationale: Valvular involvement indicates significant damage; therefore, lifelong prophylactic antibiotics are required.
Coxsackie viruses are implicated in:
- A. Herpangina
- B. Dermatitis herpetiformis
- C. Meningitis
- D. Orchitis
Correct Answer: A
Rationale: Coxsackie viruses are a common cause of herpangina. They can also cause meningitis and orchitis, but dermatitis herpetiformis is not associated with Coxsackie viruses.
Increased fetal haemoglobin is seen in:
- A. Haemoglobin H disease
- B. β-thalassaemia major
- C. Fanconi's anaemia
- D. Pyruvate kinase deficiency
Correct Answer: B
Rationale: Increased fetal haemoglobin (HbF) is a compensatory mechanism in β-thalassaemia major to counteract the reduced production of adult haemoglobin (HbA).
Injury to radial nerve involves:
- A. Abductor pollicis brevis is affected
- B. Abduction at the shoulder joint is impaired
- C. Sensory loss on the medial aspect of forearm is seen
- D. First dorsal interosseus is affected
Correct Answer: B
Rationale: Abduction at the shoulder joint is impaired