ATI Pathophysiology Test Bank Related

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In Guillain-Barre syndrome, what pathophysiologic process underlies the deficits that accompany the degeneration of myelin in the peripheral nervous system (PNS)?

  • A. The destruction of myelin results in a reduction in Schwann cell production in the client's PNS.
  • B. The lack of myelin surrounding nerve cells compromises the axonal transport system.
  • C. Without remyelination, the axon will eventually die.
  • D. A deficit of myelin makes the client more susceptible to infection by potential pathogens.
Correct Answer: C

Rationale: In Guillain-Barre syndrome, the destruction of myelin leads to axonal damage. If remyelination does not occur, the axon will eventually degenerate and die, impacting nerve function. Choice A is incorrect because the destruction of myelin does not affect Schwann cell production. Choice B is incorrect as the lack of myelin directly affects the conduction of nerve impulses, not the axonal transport system. Choice D is incorrect as a deficit of myelin does not predispose the client to infections by potential pathogens.