Nokea
Irreversible interaction of an antagonist with a receptor is due to:
- A. Ionic bonds
- B. Hydrogen bonds
- C. Covalent bonds
- D. All of the above
Correct Answer: C
Rationale: Irreversible antagonism typically involves covalent bonding, making it permanent.
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It is important to evaluate the efficacy of what parameter when evaluating the drug therapy of a patient?
- A. Appropriateness of drug dosages
- B. Compliance
- C. Caregivers knowledge level
- D. Nursing interventions
Correct Answer: D
Rationale: Evaluating nursing interventions assesses their effectiveness in achieving drug therapy goals.
The nurse administers a prescribed medication that is supplied as an enteric-coated tablet. The patient asks the nurse about this form of tablet. When describing how this tablet is absorbed, which response by the nurse would be most accurate?
- A. The medication dissolves directly from the stomach into the body.'
- B. The drug breaks up into pieces as it moves through the stomach.'
- C. The medication bypasses the GI tract and goes quickly into the bloodstream.'
- D. The drug dissolves into fragments after it reaches your small intestine.'
Correct Answer: D
Rationale: Enteric-coated tablets disintegrate or fragment after reaching the alkaline medium of the small intestine. Tablets and capsules break up into small particles and dissolve into body fluids in the gastrointestinal tract. Liquids and parenteral drugs are quickly absorbed into the body system.
Patient education when prescribing colchicine includes:
- A. Colchicine may be constipating
- B. Colchicine always causes some degree of diarrhea
- C. Mild muscle weakness is normal
- D. Moderate amounts of alcohol are safe with colchicine
Correct Answer: B
Rationale: Colchicine commonly causes diarrhea, not constipation ; weakness or alcohol aren't typical advice.
A nurse is assisting with caring for a client with cancer who is receiving cisplatin. Select the adverse effects that the nurse monitors for that are associated with this medication. (Select one that does not apply.)
- A. Tinnitus
- B. Ototoxicity
- C. Hyperkalemia
- D. Hypomagnesemia
Correct Answer: C
Rationale: Cisplatin is an alkylating medication. Alkylating medications are cell cycle phase-nonspecific medications that affect the synthesis of DNA by causing the cross-linking of DNA to inhibit cell reproduction. Cisplatin may cause ototoxicity, tinnitus, hypokalemia, hypocalcemia, hypomagnesemia, and nephrotoxicity. Amifostine (Ethyol) may be administered before cisplatin to reduce the potential for renal toxicity. Correct answers include: 1 (Tinnitus), 2 (Ototoxicity), 5 (Nephrotoxicity), 6 (Hypomagnesemia).
A nurse is providing teaching to a client who has type 2 Diabetes Mellitus and is starting Repaglinide. Which of the following statements by the client indicates understanding of the administration of this medication?
- A. I'll take this medicine with my meals.
- B. I'll take this medicine 30 minutes before I eat.
- C. I'll take this medicine just before I go to bed.
- D. I'll take this medicine as soon as I wake up in the morning.
Correct Answer: B
Rationale: Repaglinide is taken 15-30 minutes before meals to control postprandial glucose.