Least half life is for which hormone
- A. Nor adrenaline
- B. Renin
- C. Aldosterone
- D. Thyroxine
Correct Answer: A
Rationale: Noradrenaline has a very short half-life (minutes) due to rapid metabolism.
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Carvedilol is heavily metabolized by CYP2D6 and 2C9, resulting in drug interactions with which of the following drug classes?
- A. Histamine 2 blockers
- B. Quinolones
- C. Serotonin re-uptake inhibitors
- D. All of the above
Correct Answer: C
Rationale: SSRIs inhibit CYP2D6, increasing carvedilol levels and effects.
Hypoglycemic effects of repaglinide and nateglinide is determined with:
- A. Closure of ATP sensitive K+ channels
- B. Increase numbers of insulin receptors
- C. Stimulation of PPAR-Y receptors
- D. Degradation of incretin
Correct Answer: A
Rationale: Repaglinide and nateglinide close ATP-sensitive K+ channels on beta cells, triggering insulin release.
A nurse is preparing to administer a medication to a client who has absence seizures. The nurse should anticipate administering which of the following medications?
- A. Phenytoin
- B. Ethosuximide
- C. Gabapentin
- D. Carbamazepine
Correct Answer: B
Rationale: Ethosuximide , valproic acid , and lamotrigine are effective for absence seizures.
A nurse is planning to administer IV Alteplase to a client who is demonstrating manifestations of a massive Pulmonary Embolism. Which of the following interventions should the nurse plan to take?
- A. Administer IM Enoxaparin along with the Alteplase dose.
- B. Hold direct pressure on puncture sites for up to 30 min.
- C. Administer Aminocaproic acid IV prior to alteplase infusion.
- D. Prepare to administer Alteplase within 8 hr of manifestation onset.
Correct Answer: B
Rationale: Holding pressure prevents bleeding at puncture sites after alteplase, a thrombolytic.
A nurse is preparing a client's medications. Which of the following actions should the nurse take in following legal practice guidelines? (Select ONE that does not apply.)
- A. Maintain skill competency.
- B. Determine the dosage.
- C. Monitor for adverse effects.
- D. Safeguard medications.
Correct Answer: B
Rationale: Nurses must maintain competency , monitor effects , and safeguard meds ; determining dosage is the prescriber's role.