Pediatric Research Questions Related

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Many factors in nasopharyngeal carcinoma patients may affect the prognosis. Which of the following carries the worst outcome?

  • A. elevated lactate dehydrogenase (LDH) level
  • B. advanced disease
  • C. extensive cervical lymph node involvement
  • D. evidence of Epstein-Barr virus (EBV) DNA
Correct Answer: A

Rationale: Elevated LDH levels are strongly associated with aggressive disease and poor prognosis.