Nokea
One of the basic principles of chemotherapy is:
- A. Selective toxicity
- B. Accumulation in the macroorganism
- C. Causing allergies to the macroorganism
- D. None of the above
Correct Answer: A
Rationale: The correct answer is A: Selective toxicity. Chemotherapy aims to target cancer cells while minimizing harm to healthy cells, known as selective toxicity. This principle is crucial to effectively treat cancer without causing excessive damage to the patient's body. Accumulation in the macroorganism (B) and causing allergies (C) are not fundamental principles of chemotherapy and can lead to harmful side effects. Therefore, the correct answer is A as it aligns with the core objective of chemotherapy.
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Pseudomonas aeruginosa can cause:
- A. Burn wounds infection, severe pneumonia in patients with cystic fibrosis, nosocomial infections
- B. Food poisoning
- C. Bacterial pharyngitis
- D. None of the above
Correct Answer: A
Rationale: Step-by-step rationale for answer A:
1. Pseudomonas aeruginosa is known to cause burn wounds infections due to its ability to survive in moist environments.
2. It can cause severe pneumonia in patients with cystic fibrosis due to its resistance to antibiotics and ability to form biofilms.
3. It is a common cause of nosocomial infections in hospitals due to its ability to colonize medical equipment and surfaces.
Summary of other choices:
B. Pseudomonas aeruginosa typically does not cause food poisoning, as it is not a common pathogen associated with foodborne illnesses.
C. Bacterial pharyngitis is usually caused by Streptococcus pyogenes, not Pseudomonas aeruginosa, making this choice incorrect.
D. None of the above is incorrect as Pseudomonas aeruginosa is associated with specific infections mentioned in option A.
The white pulp and red pulp are part of which immune organ:
- A. Thymus
- B. Lymph node
- C. Spleen
- D. Lymphoid tissue
Correct Answer: C
Rationale: The correct answer is C: Spleen. The white pulp of the spleen contains lymphocytes that help in immune responses. The red pulp filters blood and removes old or damaged red blood cells. The thymus (A) is responsible for T cell maturation, lymph nodes (B) filter lymph, and lymphoid tissue (D) includes various lymphoid organs but does not specifically refer to the spleen's distinct white and red pulp structure. Thus, the spleen is the only organ among the choices that has both white and red pulp components essential for immune functions.
A dentist examined a 5-year-old boy and found him to have a saddle nose, high-arched palate, natiform skull. Both front maxillary incisors are peg-shaped and have a crescent-shaped notch in the cutting edge. Lymph nodes are not changed. What is the provisional diagnosis?
- A. Late congenital syphilis
- B. Early congenital syphilis
- C. Tertiary syphilis
- D. Fluorosis
Correct Answer: A
Rationale: The correct answer is A: Late congenital syphilis. The symptoms described align with late congenital syphilis, which includes saddle nose, high-arched palate, natiform skull, peg-shaped incisors, and notched cutting edge. Lymph nodes not being affected is also consistent with late congenital syphilis. Early congenital syphilis (B) typically presents with more severe symptoms at birth or shortly after. Tertiary syphilis (C) usually occurs years after initial infection and presents with different symptoms. Fluorosis (D) is caused by excessive fluoride intake and does not match the symptoms described.
Which bacterial structure helps in the movement towards or away from chemical stimuli?
- A. Flagella
- B. Pili
- C. Capsule
- D. Fimbriae
Correct Answer: A
Rationale: Flagella are the correct answer because they are long, whip-like structures that aid in bacterial movement towards or away from chemical stimuli. They rotate like propellers, allowing the bacterium to navigate its environment. Pili are used for attachment, not movement. Capsules are involved in protection and adherence, not chemotaxis. Fimbriae help in attachment to surfaces, not in movement towards stimuli.
Which of the following bacteria is a common cause of pneumonia?
- A. Streptococcus pneumoniae
- B. Mycobacterium tuberculosis
- C. Pseudomonas aeruginosa
- D. All of the above
Correct Answer: D
Rationale: The correct answer is D: All of the above.
- Streptococcus pneumoniae is a common cause of community-acquired pneumonia.
- Mycobacterium tuberculosis can cause pulmonary tuberculosis, which can present as pneumonia-like symptoms.
- Pseudomonas aeruginosa is an opportunistic pathogen that can cause pneumonia in immunocompromised individuals.
Therefore, all three bacteria can cause pneumonia, making option D the correct choice. Options A, B, and C are incorrect because they each represent a bacterium that can cause pneumonia, so only selecting one of them would not encompass all common causes of pneumonia.