Nokea
Paracetamol is an NSAID with a comparatively low anti-inflammatory effect compared to other NSAIDs.
- A. TRUE
- B. FALSE
Correct Answer: A
Rationale: Paracetamol (acetaminophen) has minimal anti-inflammatory activity, primarily acting as an analgesic and antipyretic.
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Daniel has been on 60 mg of prednisone for 10 days to treat a severe asthma exacerbation. It is time to discontinue the prednisone. How is prednisone discontinued?
- A. Patients with asthma are transitioned directly off the prednisone onto inhaled corticosteroids
- B. Prednisone can be abruptly discontinued with no adverse effects
- C. Develop a tapering schedule to slowly wean Daniel off the prednisone
- D. Substitute the prednisone with another anti-inflammatory such as ibuprofen
Correct Answer: C
Rationale: Tapering prevents adrenal suppression after high-dose prednisone; abrupt stop risks crisis.
The type of adverse drug reaction that is idiosyncratic when a drug given in the usual therapeutic doses is type:
- A. A
- B. B
- C. C
- D. D
Correct Answer: B
Rationale: Type B reactions are idiosyncratic, unpredictable responses to normal doses, unlike dose-related Type A or chronic Type C/D.
You are caring for a patient who takes several drugs. You know that those patients most likely to have adverse drug reactions are who?
- A. Patients with coronary artery disease
- B. Non-compliant patients
- C. Patients who are on the recommended dose
- D. Very young and very old patients
Correct Answer: D
Rationale: Very young and old patients have immature or declining organ function, increasing adverse reaction risk.
Adherence is improved when a drug can be given once daily. Which of the following drugs can be given once daily?
- A. Tacrine
- B. Donepezil
- C. Memantine
- D. Pyridostigmine
Correct Answer: B
Rationale: Donepezil's long half-life allows once-daily dosing, improving adherence.
The following drugs are correctly paired with a clinical use EXCEPT:
- A. Danazol to treat endometriosis
- B. Flutamide to treat benign prostatic hyperplasia
- C. Finasteride to treat male pattern baldness
- D. Clomiphene to treat anovulatory infertility
Correct Answer: B
Rationale: Flutamide treats prostate cancer, not BPH; finasteride is used for BPH.