Patient education when prescribing colchicine includes:
- A. Colchicine may be constipating
- B. Colchicine always causes some degree of diarrhea
- C. Mild muscle weakness is normal
- D. Moderate amounts of alcohol are safe with colchicine
Correct Answer: B
Rationale: Colchicine commonly causes diarrhea, not constipation ; weakness or alcohol aren't typical advice.
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A nurse in an acute care facility is caring for a client who is receiving IV Nitroprusside for hypertensive crisis. The nurse should monitor the client for which of the following adverse reactions to this medication?
- A. Intestinal ileus
- B. Neutropenia
- C. Deurium
- D. Hyperthermia
Correct Answer: C
Rationale: Nitroprusside can cause delirium (C, likely typo for delirium), a CNS side effect in toxicity.
Potentially fatal granulocytopenia has been associated with treatment of hyperthyroidism with propylthiouracil. Patients should be taught to report:
- A. Tinnitus and decreased salivation
- B. Fever and sore throat
- C. Hypocalcemia and osteoporosis
- D. Laryngeal edema and difficulty swallowing
Correct Answer: B
Rationale: Fever and sore throat signal granulocytopenia with propylthiouracil; other symptoms are unrelated.
The nurse administers a prescribed medication that is supplied as an enteric-coated tablet. The patient asks the nurse about this form of tablet. When describing how this tablet is absorbed, which response by the nurse would be most accurate?
- A. The medication dissolves directly from the stomach into the body.'
- B. The drug breaks up into pieces as it moves through the stomach.'
- C. The medication bypasses the GI tract and goes quickly into the bloodstream.'
- D. The drug dissolves into fragments after it reaches your small intestine.'
Correct Answer: D
Rationale: Enteric-coated tablets disintegrate or fragment after reaching the alkaline medium of the small intestine. Tablets and capsules break up into small particles and dissolve into body fluids in the gastrointestinal tract. Liquids and parenteral drugs are quickly absorbed into the body system.
The patient looks at the prescription provided by the doctor and asks the nurse whether he can request a generic substitution. The nurse answers No when noting what on the prescription?
- A. No refills
- B. DAW
- C. Brand name used on prescription
- D. Patient older than 65 years of age
Correct Answer: B
Rationale: DAW stands for dispense as written and means that the doctor does not want a generic substituted for the prescribed medication. Requesting no refills does not preclude the substitution of a generic medication. Even when the brand name is ordered, the pharmacist can substitute a generic equivalent so long as the prescriber does not write DAW. Generic substitutions are not impacted by the patients age.
Osteoporosis is a major adverse effect caused by the glucocorticoids. It is due to their ability to:
- A. Increase the excretion of calcium
- B. Inhibit absorption of calcium
- C. Stimulate the hypothalamic-pituitary-adrenal axis
- D. Decrease production of prostaglandins
Correct Answer: B
Rationale: Glucocorticoids inhibit calcium absorption in the gut, contributing to osteoporosis.
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