Nokea
Poxviruses are DNA viruses that replicate in the cytoplasm.
- A. TRUE
- B. FALSE
- C. Partially
- D. Not Sure
Correct Answer: A
Rationale: Step 1: Poxviruses are indeed DNA viruses, confirmed by scientific research.
Step 2: Poxviruses replicate entirely in the cytoplasm, unlike most DNA viruses.
Step 3: Cytoplasmic replication is a unique characteristic of poxviruses.
Step 4: The replication process of poxviruses in the cytoplasm is well-documented.
Step 5: Therefore, option A (TRUE) is correct, as poxviruses replicate in the cytoplasm exclusively.
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Which structure in bacteria is used for attachment to surfaces?
- A. Flagella
- B. Fimbriae
- C. Pili
- D. Capsule
Correct Answer: B
Rationale: The correct answer is B: Fimbriae. Fimbriae are short, hair-like appendages on the surface of bacteria that help in attachment to surfaces. They aid in colonization and biofilm formation. Flagella (A) are used for motility. Pili (C) are longer appendages used for conjugation and adherence to other cells. Capsules (D) are protective structures that aid in evading the host immune system, not necessarily for attachment.
The organisms to be identified have a nucleus surrounded by a nuclear membrane. Genetic material is concentrated predominantly in the chromosomes which consist of DNA strands and protein molecules. These cells divide mitotically. Identify these organisms:
- A. Eukaryotes
- B. Bacteriophages
- C. Prokaryotes
- D. Viruses
Correct Answer: A
Rationale: Step-by-step rationale:
1. The presence of a nucleus with a nuclear membrane indicates eukaryotic cells.
2. Eukaryotes have genetic material in chromosomes made of DNA and proteins.
3. Mitotic division is characteristic of eukaryotic cells.
4. Therefore, the organisms described are eukaryotes.
Summary:
- Bacteriophages (B) are viruses that infect bacteria.
- Prokaryotes (C) lack a nucleus and their genetic material is not organized into chromosomes.
- Viruses (D) are not considered living organisms and do not have a nucleus or chromosomes.
A patient with severe pneumonia had a sputum culture revealing Gram-negative rods that are non-lactose fermenters. What is the most likely causative agent?
- A. Pseudomonas aeruginosa
- B. Escherichia coli
- C. Klebsiella pneumoniae
- D. Enterobacter cloacae
Correct Answer: A
Rationale: The correct answer is A: Pseudomonas aeruginosa. This is because Pseudomonas aeruginosa is a common Gram-negative rod that is a non-lactose fermenter and a common cause of severe pneumonia, especially in immunocompromised individuals. It is also known for its resistance to many antibiotics, making it difficult to treat.
Summary of other choices:
B: Escherichia coli is a lactose fermenter and is not commonly associated with severe pneumonia.
C: Klebsiella pneumoniae is a lactose fermenter and is more commonly associated with pneumonia in alcoholics or debilitated patients.
D: Enterobacter cloacae is a lactose fermenter and is not a common cause of severe pneumonia.
A 6-year-old boy is brought to the pediatrician by his mother, who complains of low-grade fever, chronic cough and night sweats in her child. She describes the cough as productive, producing white sputum that is sometimes streaked with blood. She also says that her son has lost some weight in the last month. His vital signs include blood pressure of 115/75 mm Hg, heart rate of 110/min., respiratory rate of 18/min. and temperature of 36,6°C. On physical examination, the patient is ill looking. Pulmonary auscultation reveals some fine crackles in the right upper lobe. The pediatrician suspects an active infection and performs Mantoux test. Intradermal injection of which of the following substances has been most likely used by pediatrician for screening test in this clinical case?
- A. Tuberculin
- B. Measles
- C. Tetanus and diphtheria toxoids vaccine (Td)
- D. Bacillus Calmette-Guerin (BCG) vaccine
Correct Answer: A
Rationale: The correct answer is A: Tuberculin. In this clinical scenario, the patient presents with symptoms suggestive of tuberculosis, including chronic cough, night sweats, weight loss, and hemoptysis. The Mantoux test, also known as the tuberculin skin test, is used to screen for tuberculosis. Tuberculin, a purified protein derivative (PPD) derived from Mycobacterium tuberculosis, is injected intradermally. The test elicits a delayed-type hypersensitivity reaction in individuals who have been exposed to the organism in the past. A positive Mantoux test indicates exposure to tuberculosis and does not differentiate between active infection and prior exposure.
Explanation for other choices:
B: Measles - Measles is a viral infection that presents with a characteristic rash and fever, not consistent with the symptoms described in the case.
C: Tetanus and diphtheria toxoids vaccine (Td) - Td vaccine is not used for tuberculosis screening and does not elicit
An 18-year-old patient has developed candidiasis after the case of pneumonia treated with β-lactam antibiotic. What antimycotic agent should be prescribed?
- A. Fluconazole
- B. Streptomycin
- C. Phthalylsulfathiazole
- D. Ampicillin
Correct Answer: A
Rationale: The correct answer is A: Fluconazole.
1. Fluconazole is an antifungal agent effective against Candida species commonly causing candidiasis.
2. Streptomycin (B) is an antibiotic used for bacterial infections, not fungal.
3. Phthalylsulfathiazole (C) is an antibacterial agent, not antifungal.
4. Ampicillin (D) is a β-lactam antibiotic, which can actually contribute to fungal infections like candidiasis.