Nokea
Pregnant patients who are taking isoniazid (INH) should take 25 mg/day of vitamin B6 (pyridoxine) to prevent:
- A. Beriberi
- B. Peripheral neuropathy
- C. Rickets
- D. Megaloblastic anemia
Correct Answer: B
Rationale: Vitamin B6 supplementation prevents INH-induced peripheral neuropathy.
You may also like to solve these questions
The volume of distribution (Vd) for a drug that is completely retained in the vascular compartment would be?
- A. High
- B. Low
- C. Unchanged
- D. Cannot be determined
Correct Answer: B
Rationale: A drug confined to the vascular compartment (e.g., plasma) has a low Vd, close to plasma volume (about 0.06 L/kg), indicating limited distribution.
Attenuated vaccines are also known as:
- A. Killed vaccines
- B. Booster vaccines
- C. Inactivated vaccines
- D. Live vaccines
Correct Answer: D
Rationale: Attenuated vaccines are live, weakened forms, unlike killed/inactivated or booster-specific vaccines.
Patients who are on chronic long-term corticosteroid therapy need education regarding:
- A. Receiving all vaccinations, especially the live flu vaccine
- B. Reporting black tarry stools or abdominal pain
- C. Eating a high carbohydrate diet with plenty of fluids
- D. Small amounts of alcohol are generally tolerated
Correct Answer: B
Rationale: Black tarry stools signal GI bleeding from corticosteroids; live vaccines are contraindicated.
Nicotine replacement therapy (NRT):
- A. Is widely distributed in the body only when the gum products are used
- B. Does not cross the placenta and so is safe for pregnant women
- C. Delays healing of esophagitis and peptic ulcers
- D. Has no drug interactions when a transdermal patch is used
Correct Answer: C
Rationale: NRT delays GI ulcer healing due to nicotine's effects on acid secretion.
Characteristics of vitamin D and its metabolites include which of the following?
- A. Act to decrease serum levels of calcium
- B. Activation of vitamin D receptors in the major cells of
- C. Calcitriol is the major derivative responsible for increasing intestinal absorption of phosphate
- D. Metabolites of vitamin D increase renal excretion of calcium
Correct Answer: C
Rationale: Calcitriol increases intestinal absorption of calcium and phosphate.