Roach's Introductory Clinical Pharmacology 11th Edition - Antibacterial Drugs That Interfere With DNA/RNA Synthesis Related

Review Roach's Introductory Clinical Pharmacology 11th Edition - Antibacterial Drugs That Interfere With DNA/RNA Synthesis related questions and content

Prior to administration of moxifloxacin (Avelox), a nurse obtains a medication history. Use of which drug would alert the nurse to contact the prescriber because concomitant use would lead to an increased risk for a severe cardiac arrhythmia? Select all that apply.

  • A. Amiodarone (Pacerone)
  • B. Glyburide (DiaBeta)
  • C. Solaid (Betapace)
  • D. Procainamide (Procanbid)
  • E. Ibuprofen (Motrin)
Correct Answer: A,C,D

Rationale: There is a risk of severe cardiac arrhythmias when moxifloxacin (Avelox) is administered with drugs that increase the QT interval, such as quinidine, procainamide, amiodarone, or sotalol.