Proteins found in muscle fibres include:
- A. Vimentin
- B. Saccharin
- C. Keratin
- D. Desmin
Correct Answer: D
Rationale: Desmin: Desmin is an intermediate filament protein found in muscle fibers, playing a critical role in maintaining structural integrity and organization within muscle cells.
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In neonates with anomalous total pulmonary venous return and obstruction, the chest x-ray demonstrates
- A. heart enlarged
- B. prominent pulmonary artery
- C. prominent right ventricle
- D. prominent subaortic stenosis
Correct Answer: D
Rationale: Prominent subaortic stenosis is not typically seen in TAPVR.
In normal neonates:
- A. Extracellular fluid volume exceeds intracellular fluid volume
- B. In a term baby, plasma calcium levels exceed that of the mother
- C. Clamping the umbilical cord after cessation of cord pulsations increases the blood volume by 20% in the baby
- D. There are two arteries and one vein in the umbilical cord
Correct Answer: A
Rationale: In neonates, extracellular fluid volume is greater than intracellular fluid volume, reflecting the transition from intrauterine to extrauterine life.
In systemic mastocytosis:
- A. Areas of depigmentation occur
- B. Intermittent flushing is seen
- C. IgE levels are high
- D. Is relieved by aspirin
Correct Answer: B
Rationale: Intermittent flushing is a recognized symptom of systemic mastocytosis due to the release of histamine and other chemicals from mast cells.
Dome and dart P wave in lead V1 in electrocardiogram is suggestive of which of the following?
- A. Dextrocardia
- B. Left atrial ectopic rhythm
- C. Biatrial enlargement
- D. Mitral stenosis
Correct Answer: C
Rationale: The dome and dart P wave morphology is characteristic of biatrial enlargement, often seen in conditions like mitral stenosis and atrial fibrillation.
Causes of a discrete osteolytic bone lesion in a two-year-old include:
- A. Rickets
- B. Non-accidental injury
- C. Eosinophilic granuloma
- D. Acute lymphoblastic leukaemia
Correct Answer: C
Rationale: Eosinophilic granuloma is a benign bone lesion that can present with osteolytic lesions, typically seen in children as part of Langerhans cell histiocytosis.