Regarding cisapride:
- A. It is licensed for use in children
- B. Fatal arrhythmias have been reported
- C. Concurrent administration with erythromycin is not advised
- D. It commonly causes constipation
Correct Answer: B
Rationale: Fatal arrhythmias have been reported: Cisapride, a gastrointestinal prokinetic agent, has been linked to fatal arrhythmias, particularly when combined with certain drugs like erythromycin.
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Afterload reducers are not indicated in children with heart failure secondary to
- A. cardiomyopathy
- B. severe mitral insufficiency
- C. aortic stenosis
- D. ventricular septal defect
Correct Answer: C
Rationale: Afterload reducers are contraindicated in conditions where forward flow is already compromised, such as aortic stenosis.
A 15-year-old female reports fainting at school in class on two occasions. The adolescent's orthostatic blood pressures are normal. The primary care pediatric nurse practitioner suspects a cardiac cause for these episodes and will order which tests before referring her to a pediatric cardiologist?
- A. 12-lead electrocardiogram
- B. Echocardiogram
- C. Tilt table testing
- D. Treadmill exercise testing
Correct Answer: A
Rationale: A 12-lead ECG is useful for initial evaluation.
22q11 deletion is commonly associated with all except
- A. Tetralogy of Fallot
- B. Truncus arteriosus
- C. Interrupted aortic arch
- D. D-Transposition of great arteries
Correct Answer: D
Rationale: 22q11 deletion is not commonly associated with D-Transposition of great arteries.
Type I renal tubular acidosis:
- A. Only occurs in children
- B. Is caused by a failure of ammonium ion secretion
- C. Is associated with renal calcification
- D. Typically leads to hypovolaemia
Correct Answer: B
Rationale: Type I renal tubular acidosis is characterized by a failure in ammonium ion secretion, leading to a failure to acidify urine, which can result in metabolic acidosis.
Coarctation of aorta is:
- A. Commonly associated with Turner's syndrome
- B. Inherited as autosomal dominant
- C. Associated with intracranial aneurysms
- D. Excluded from the diagnosis in the presence of femoral pulses
Correct Answer: A
Rationale: Coarctation of the aorta is commonly associated with Turner's syndrome, a chromosomal condition affecting females.
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